Table 1

Inclusion and exclusion criteria

Inclusion criteria	Exclusion criteria
1. Adult men or women	1. Participant under prescription for medication for digestive symptoms such as antispasmodic, laxatives and antidiarrhoeic drugs or other digestive auxiliaries
2. Age 18–60 years	2. Relevant history, presence of any medical disorder or intake of medication/dietary supplements, potentially interfering with this trial at screening
3. Healthy volunteers free of chronic diseases with relevant effect on the gastrointestinal system or on visceral motility	3. Participants with stool frequency of ≤1 stool every 7 days
4. Without a diagnosis of any digestive disease including functional bowel disorders such as IBS	4. Participants not willing to avoid prebiotics and probiotics for the duration of the study
5. Non-diabetic, no gastric bypass surgery	5. Intake of antibiotics in the past 4 weeks and laxatives in the past 2 weeks
6. Fasting plasma glucose (finger-stick) <100 mg/dL (<5.5 mmol/L)	6. Current use of medication for lowering blood cholesterol or glucose
7. Non-smoker	7. Change of dietary habits within the 4 weeks prior to screening (for instance, start of a diet high in fibre)
8. Willing and able to provide written informed consent	8. Pregnant participant or participant planning to become pregnant during the study; breastfeeding participant
	9. Participants with a history of drug, alcohol or other substance abuse, or other factors limiting their ability to cooperate during the study
	10. Participants anticipating a change in their lifestyle or physical activity levels since this may also influence the results
	11. Known food intolerance or allergy
	12. Participant involved in any clinical or food study within the preceding month

IBS, irritable bowel syndrome.