N=7052 | Quintiles of Whiteley Index (corresponding scores on Whiteley Index) | p Value for trend | ||||
---|---|---|---|---|---|---|
1st (14–16) | 2nd (17–19) | 3rd (20–22) | 4th (23–25) | 5th (≥26) | ||
N events (%) | 16 (1.7) | 48 (2.9) | 43 (3.0) | 58 (3.7) | 69 (4.6)) | |
HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | <0.001* | |
Adjusted for gender | (ref) | 1.82 (1.04 to 3.21) | 1.95 (1.10 to 3.47) | 2.43 (1.40 to 4.23) | 3.06 (1.78 to 5.28) | <0.001 |
Adjusted for gender and sociodemographic factors† | (ref) | 1.83 (1.04 to 3.22) | 1.94 (1.09 to 3.44) | 2.34 (1.34 to 4.07) | 2.86 (1.66 to 4.94) | <0.001 |
Adjusted for CVD risk factors‡ | (ref) | 1.67 (0.93 to 3.00) | 1.70 (0.93 to 3.09) | 2.14 (1.21 to 3.80) | 2.36 (1.33 to 4.17) | 0.001 |
Adjusted for all covariates§ | (ref) | 1.66 (0.93 to 2.99) | 1.71 (0.94 to 3.11) | 2.13 (1.20 to 3.78) | 2.35 (1.33 to 4.16) | 0.002 |
Estimates are adjusted separately for blocks of covariates and all covariates combined.
*Linear by linear association.
†Gender, cohabiting and education.
‡Gender, alcohol consumption, physical activity, diabetes, BMI, first-degree relative with AMI before 60 years, smoking, total cholesterol, HDL cholesterol, systolic blood pressure.
§Gender, cohabiting, education, alcohol consumption, physical activity, diabetes, BMI, first-degree relative with AMI before 60 years, smoking, total cholesterol, HDL cholesterol, systolic blood pressure.