Table 1

Identified systematic reviews (n=60) classified by patient-safety area (n=14)

Patient-safety areaNumber of systematic reviews (references)Intervention components relevant to patient safety (effective components are in bold)
Adverse drug eventSubarea
CPOE system222 23CPOE system
Medication review424–27Medication reconciliation
Computer-assisted decision support/alerts328–30Computerised advice or decision support; computerised drug-laboratory alerts for clinicians on prescribing or monitoring decisions
Multicomponent interventions631–36Multicomponent interventions, including pharmacist involvement and support of care teams or physicians; guideline implementation, including academic detailing, reminders and feedback of data; multicomponent intervention, including CPOE system, changes in work schedules, education, support systems for clinical decision-making
Infection*Device-related infections (CAUTI; CLABSI; VAP)437–40Care bundles and checklists; empowerment to stop procedure; surveillance; infrastructure and organisational changes; training on appropriate catheter placement; catheter restriction and removal protocols; reminder or stop order to decrease catheter placement; use of specific technologies
Sepsis141Multicomponent programme aimed at improving compliance to sepsis care bundles, including education and decision support tools
Hand-hygiene compliance242 43Education; audit and feedback; health promotion; variations in the availability and type of products used for hand hygiene
Overall hospital-acquired infection144Education; protocols to remove catheters
Delirium745–51Psychiatric assessment; special care; daily visits by a liaison nurse; interdisciplinary team; supportive psychotherapy; multicomponent intervention, including cognitive screening, proactive geriatric consultation and psychotherapy; multicomponent intervention, including early mobility, cognition and orientation, sleep–wake cycle preservation; multicomponent intervention, including physiotherapy, family involvement and staff/family-member education
Adverse event after hospital discharge or clinical handover752–58Postacute intermediate care units; geriatric assessment; liaison nurse; predischarge assessment of risks; patient engagement; individualised patient record; multidisciplinary discharge planning team; clinical follow-up; nurse-led early-discharge planning programmes
Fall459–62Addressing risk factors by a multidisciplinary team; care planning; environmental changes; movement alarms; physiotherapy; management of urinary incontinence; multicomponent interventions, including risk alert card, exercise, education, hip protectors and geriatric assessment
Adverse event in surgery563–67Screening and decolonisation of surgical-site infections; subspecialisation; benchmarking; technology or training; surgical safety checklist
Cardiopulmonary arrest468–71Critical-care outreach service; rapid response teams
Venous thromboembolism272 73Alerts and education; real-time audit and feedback; multicomponent interventions to improve appropriate administration of thromboprophylaxis
Staffing374–76Increasing proportion of support staff; addition of specialist nursing post to staffing; reducing shift length; protected sleep time; night float; education among residents; interdisciplinary team interventions
Pressure ulcer177Standardisation of interventions; multidisciplinary teams and leadership; designated skin champions; education; audit and feedback
Mechanical complication and underfeeding178Total parenteral nutrition team: nutrition support for patients who are unable to obtain adequate nutrition either via the oral or enteral route
Clinical pathway179Clinical pathways: multidisciplinary care plans with essential steps in care, supporting the translation of clinical guidelines into local protocols and application in practice
Safety culture180Error-prevention training; restructured patient-safety governance; lessons-learnt programme; cause analysis programme; executive rounds
External inspection181External inspections of compliance with standards (eg, accreditation)
  • *Surgical-site infections were classified as ‘prevention of adverse events in surgery’.

  • CAUTI, catheter-associated urinary tract infection; CLABSI, central-line-associated bloodstream infection; CPOE, computerised physician order entry; VAP, ventilator-associated pneumonia.