TAPS Project eligibility criteria
| PrEP arm | ITx arm |
|---|---|
| 18 years or older | 18 years or older |
| Creatinine clearance above 60.0 mL/min | Creatinine clearance above 60.0 mL/min |
| Negative for hepatitis B | CD4 count above national standard for ART initiation |
| Not pregnant | Not pregnant |
| Not presenting signs or symptoms of or taking medication for MDR-TB | Not presenting signs or symptoms of or taking medication for MDR-TB |
| Not prescribed other drugs contraindicated for taking with emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) | Not prescribed other drugs contraindicated for taking with tenofovir disoproxyl fumarate/lamivudine/emtricitabine/efavirenz (TDF+3TC/FTC+EFV) |
ART, antiretroviral therapy; ITx, immediate treatment; MDR-TB, multidrug resistant tuberculosis; PrEP, pre-exposure prophylaxis.