Association between hypoglycaemia and mortality
| OR (95% CI) | p Value | |
|---|---|---|
| Crude model | ||
| No hypoglycaemia during follow-up | (Reference) | |
| Only mild hypoglycaemia during follow-up | 0.37 (0.23 to 0.59) | <0.01 |
| Severe hypoglycaemia during follow-up | 0.69 (0.31 to 1.54) | 0.36 |
| Adjusted model* | ||
| No hypoglycaemia during follow-up | (Reference) | |
| Only mild hypoglycaemia during follow-up | 0.48 (0.28 to 0.80) | <0.01 |
| Severe hypoglycaemia during follow-up | 0.76 (0.33 to 1.80) | 0.52 |
*Adjusted for age, sex, diabetes duration (</≥10 years), HbA1c level (<7% (<53 mmol/mol)/≥7% (53 mmol/mol)), hypertension (SBP≥140 mm Hg, DBP≥90 mm Hg or use of antihypertensive medication), smoking, use of sulfonylurea, and microvascular or macrovascular complications (defined as retinopathy, history of CVD, eGFR value <60 or UACR≥3.5 mg/mmol for women or ≥2.5 mg/mmol for men).
CVD, cardiovascular disease; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HbA1c, glycated haemoglobin; SBP, systolic blood pressure; UACR, urinary albumin–creatinine ratio.