Table 3

Distribution of indicators per end-of-life trajectory

 End of life trajectory
All patientsCancerOrgan failure (pulmonary+heart+liver+renal)Dementia+chronic neurological diseasesAdvanced frailty
No advanced disease criteria
p Value
n=782n=76 (9.7%)N=126 (16.1%)n=203 (26%)n=377 (48.2%)
Domainn%n%n%n%n%
Functional
S (Barthel <25)14722.234.565.310149.73710.6<0.005
P (loss ≥2ADL's)24331.53343.43830.66331.0310929.40.121
P (clinical perception)34344.34559.25442.98441.4160430.050
Nutritional
S (albumin <2.5)245.858.166.410.4135.90.560
P (Weight loss >10%)4212.2723.3611.5146.8159.70.211
P (clinical perception)237 30.74863.229236331.39726.3<0.005
Cognitive
S (GDS ≥6c)16921.9000016983.200<0.005
P (loss ≥2ADL's)688.7na nanana6833.5nana<0.005
Emotional
 Distress16521.92024.72822.63316.28423.80.134
Geriatric syndromes
 Pressure ulcers344.43410.8199.3113<0.005
 Dysphagia8110.4810.843.24823.6215.6<0.005
 Falls >28611.279.597.32612.844120.401
 Delirium12215.71013.21713.53818.75715.30.518
 Rec. infections415.3341411.283.9164.30.015
Others
 Comorbidity (Charlson average)3.23 (±2.9)5.34 (±2.6)3.38 (±2.1)2.28 (±1.7)3.07 (±2.2)<0.005
 Use of resources
  Unplanned admissions (average, per year)0.55 (±1.0)0.64 (±0.9)1.0 (±1.3)0.22 (±0.5)0.5 (±1.15)<0.005
  Complex care14519.22635.12722.12813.86417.9<0.005
 Palliative care approach
  Choice/demand patient445.61317.175.631.4215.6<0.005
  Choice/demand family20926.73039.53023.86934.08021.5<0.005
  Need (healthcare professionals)12115.53647.42116.92713.33710<0.005
 Age (mean)80.89 (±11.9)79.9 (±24.0)77.7 (±13.4)82.99 (±9.7)82.6 (±11.3)<0.005
 Sex
  Male30138.54457.96652.45024.614137.4<0.005
  Women48161.53242.16047.615375.423662.6
  • %, Percentage of patients with the presence of the analysed variable with respect to the total of patients (once missing data excluded).

  • p Values: obtained from comparative analysis among the four groups described: cancer, organ failure, dementia/chronic neurological diseases in advanced frailty.

  • ADL, activities of daily living; n, number of valid patients for evaluation of variable; na, not applicable; P, progression criteria; S, severity criteria.