Characteristics of included systematic reviews
| Review ID | Funding source | Search period/end date | Perspective reported | Populations of interest | Included vaccines | Included study designs | No. of relevant studies | ||
|---|---|---|---|---|---|---|---|---|---|
| Occupational health | Employer | Patient safety | |||||||
| Burls et al13 | European Scientific Working Group on Influenza | Until June 2004 | Yes (HCWs) | Yes | Yes | HCW; patients (high risk) | Any | All | 5 |
| Michiels et al14 | National Institute for Health and Disability Insurance in Belgium | January 2006 to March 2011 | Yes (HCWs and healthy adults) | Yes | Yes | HCW; healthy adults (16–65 years); patients (no further definition) | Trivalent inactivated | RCTs and non-RCT | 10 |
| Ng and Lai12 | None stated | Date of launch to March 2011 | Yes (HCWs) | Yes | No | HCW | Any | RCTs and non-RCTs | 3 |
| Demicheli et al19 | None stated | Date of launch to May 2013 | Yes (healthy adults) | Yes | No | Healthy adults (16–65 years) | Inactivated parenteral | RCTs and quasi-RCTs | 20 |
| DiazGranados et al15 | Authors employees of Sanofi Pasteur | Until October 2011 | Yes (healthy adults) | No | No | Healthy adults (non-elderly) | Inactivated parent, live attenuated intranasal, adjuvant or recombinant | RCTs and quasi-RCTs | 20 |
| Ferroni and Jefferson16 | None stated | Date of launch to March 2011 | Yes (healthy adults) | Yes | Yes | Patients (no further definition); healthy adults | Any | SRs and RCTs | 6 |
| Osterholm et al17 | Alfred P Sloan Foundation | January 1967 to February 2011 | Yes (healthy adults) | No | No | Healthy adults (18–46 years) | Any | RCTs and observational studies | 7 |
| Villari et al18 | Italian Ministry of Health and the Emilia Romagna Regional Health Agency | January 1966 December 2002 | Yes (healthy adults) | No | No | Healthy adults (mainly 16–65 years) | Any | RCTs and quasi-RCTs | 26 |
| Ahmed et al22 | None stated | January 1948 to June 2012 | No | No | Yes | Patients in healthcare facilities | Inactivated or live attenuated | RCTs, cohort, case–control studies | 6 |
| Dolan et al23 | WHO Global Influenza Programme | Not stated | No | No | Yes | Patients (at high risk of respiratory infection) | Any | RCTs and observational studies (cross sectional/cohort) | 16 |
| Thomas et al21 | None stated | Date of launch to March 2013 | No | No | Yes | Patients (aged >60 years living in institutions) | Any | RCTs and non-RCTs | 3 |
HCWs, healthcare workers; RCTs, randomised controlled trials; SRs, systematic reviews.