Table 1

Patient characteristics at presentation to the acute medical service

Non-IDP (N=241)IDP (N=56)
CharacteristicsN (%) or median (IQR)N (%) or median (IQR)p Value
Age72 (52–82)79 (62–83)0.15
Female137 (57)30 (54)0.66
Charlson score1 (1–2)1 (1–2)0.97
Ischaemic heart disease34 (14%)6 (11%)0.50
Congestive cardiac failure18 (7%)5 (9%)0.71
Pulmonary disease64 (27%)10 (18%)0.18
Cerebrovascular disease24 (10%)3 (5%)0.44
Dementia13 (5%)7 (12%)0.06
Renal disease25 (10%)6 (11%)0.94
Liver disease5 (2%)0 (0%)0.59
Cancer19 (8%)5 (9%)0.80
Immunosuppression*7 (3%)4 (7%)0.13
Sepsis†20 (8%)5 (9%)0.88
Community antibiotic therapy39 (16%)11 (20%)0.53
Fever on admission17 (7%)5 (9%)0.63
C reactive protein14 (3–60)14 (5–70)0.94
White cell count (10^9/l)8 (7–11)8 (6–10)0.03
Weekend admission57 (24%)9 (16%)0.22
Night-time admission58 (24%)17 (30%)0.33
Admission with frailty syndrome‡28 (12%)12 (21%)0.05
  • p Values calculated using Wilcoxon rank sum tests for continuous variables and χ2 tests for categorical variables, unless any cell number was <5 or cell percentage <5% in which case Fisher’s exact test was used.

  • *Immunosuppression defined as HIV infection, haematological malignancy, other malignancy, renal failure, previous transplant, chemo/radiotherapy in past 5 years, immunosuppressive drugs, systemic corticosteroids (0.5 mg/kg/day for >14 days). †Sepsis defined as per the American Society of Critical Care Medicine as fulfilling Systemic Inflammatory Response Syndrome (SIRS) criterion of 2 or more of: respiratory rate >20, pulse >90, leucocytes <4 or >12, temperature <36°C or >38°C with an infective source.

  • ‡Frailty syndrome as defined by the British Geriatric Society22—falls, immobility, delirium/dementia, polypharmacy, incontinence, end-of-life care.

  • IDP, infectious diseases physician.