Table 1

Characteristics and relative risks of severe sepsis among pregnant and recently pregnant women

TotalCritical care admissionsAll maternitiesRelative risk (95% CI)
646 (100.0)2 186 818
Recently pregnant413 (63.9)
Maternal age, years (mean; SD)28.3 (6.9)29.0 (–)
 <2080 (12.4)129 167 (5.9)2.5 (1.9 to 3.3)
 20–24133 (20.6)419 944 (19.2)1.3 (1.0 to 1.6)
 25–29148 (23.0)602 716 (27.6)1
 30–34153 (23.7)600 694 (27.5)1.0 (0.8 to 1.3)
 35–3995 (14.7)352 364 (16.1)1.1 (0.9 to 1.4)
 ≥4036 (5.6)81 933 (3.7)1.8 (1.2 to 2.6)
Non-white ethnicity154 (23.8)609 250 (27.9)0.9 (0.8 to 1.0)
Index of multiple deprivation (quintiles)*
 1 (least deprived)63 (10.1)589 784 (27.6)1
 275 (12.0)475 573 (22.2)1.5 (1.1 to 2.1)
 3109 (17.5)395 137 (18.5)2.6 (1.9 to 3.5)
 4148 (23.8)346 002 (16.2)4.0 (3.0 to 5.4)
 5 (most deprived)228 (36.6)330 916 (15.5)6.5 (4.9 to 8.5)
BMI, kg/m2 (median; IQR)* (N=312)26 (22–30)
History of immunosuppression15 (2.3)
Weeks gestation
 Antenatal (median; IQR)26 (20–31)
 Postnatal (median; IQR)38 (31–41)
Recently pregnant women only
Parity*
 0193 (48.4)
 196 (24.1)
 ≥2110 (27.6)
Assisted conception*24 (8.1)
Mode of delivery†
 Spontaneous vaginal98 (25.9)1 334 242 (61.0)1
 Assisted vaginal28 (7.4)273 340 (12.5)1.4 (0.9 to 2.1)
 Caesarean section242 (64.0)535 999 (24.5)6.2 (4.9 to 7.8)
 Unknown10 (2.7)
All multiple births (live births and stillbirths)28 (7.6)34 663 (1.6)4.4 (3.1 to 6.3)
Pregnancy outcomes
 Live births321 (77.7)
 Stillbirths47 (11.4)11 697 (0.5%)21.3 (16.3 to 27.9)
 1st/2nd trimester loss25 (6.1)
 Ectopic pregnancy10 (2.4)
 Other‡2 (0.5)
 Unknown10 (2.4)
Hysterectomy*20 (5.4)
Days since delivery (median; IQR)3 (0–8)
  • Bold typeface indicates statistically significant results. Figures are N (%) unless otherwise stated.

  • 1=Reference Group.

  • *Of those reported.

  • †National rates are total deliveries.

  • ‡Two women each had one live birth and one stillbirth from the most recent pregnancy.

  • BMI, body mass index.