Sensitivity, specificity, PPV, NPV and κ for automated urinalysis versus the laboratory reference test (Urisys 2400), as well as for visual urinalysis versus the laboratory reference method
| Urisys 2400 | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | κ (0.95 CI) | |||
|---|---|---|---|---|---|---|---|---|
| Visual | ||||||||
| Nitrite | Positive | Negative | ||||||
| N=234 | Positive | 44 | 14 | 96% (85% to 99%) | 93% (88% to 96%) | 76% (63% to 86%) | 99% (96% to 100%) | 0.803 (0.710 to 0.896) |
| Negative | 2 | 174 | ||||||
| Automated | ||||||||
| Nitrite | ||||||||
| N=227 | Positive | 40 | 9 | 91% (78% to 97%) | 95% (91% to 98%) | 82% (68% to 91%) | 98% (94% to 99%) | 0.824 (0.732 to 0.917) |
| Negative | 4 | 174 | ||||||
| Visual | ||||||||
| Leucocytes | Positive | Negative | ||||||
| N=234 | Positive | 125 | 5 | 61% (54% to 67%) | 82% (63% to 94%) | 96% (91% to 99%) | 22% (15% to 31%) | 0.197 (0.062 to 0.332) |
| Negative | 81 | 23 | ||||||
| Automated | ||||||||
| Leucocytes | ||||||||
| N=227 | Positive | 130 | 4 | 65% (58% to 72%) | 86% (67% to 96%) | 97% (93% to 99%) | 26% (17% to 36%) | 0.256 (0.115 to 0.396) |
| Negative | 69 | 24 | ||||||
| Visual | ||||||||
| Erythrocytes | Positive | Negative | ||||||
| N=230 | Positive | 79 | 8 | 56% (47% to 64%) | 91% (83% to 96%) | 91% (83% to 96%) | 56% (47% to 64%) | 0.416 (0.303 to 0.529) |
| Negative | 63 | 80 | ||||||
| Automated | ||||||||
| Erythrocytes | ||||||||
| N=229 | Positive | 91 | 8 | 65% (56% to 73%) | 91% (83% to 96%) | 92% (85% to 96%) | 62% (53% to 71%) | 0.517 (0.408 to 0.626) |
| Negative | 49 | 81 | ||||||
NPV, negative predictive value; PPV, positive predictive value.