Table 4

HRs of the predictors of influenza vaccination rate among children and adolescents with high-risk medical conditions; presentation by age group

	2–3 year olds		4–8 year olds		9–17 year olds
	Estimate 95% CI	p Value	Estimate 95% CI	p Value	Estimate 95% CI	p Value
Season
2012–2013	1.00*		1.00*		1.00*
2013–2014	1.83 (1.69 to 1.97)		1.14 (1.10 to 1.19)		1.06 (1.04 to 1.09)
2014–2015	1.52 (1.40 to 1.65)	<0.001	1.07 (1.04 to 1.12)	<0.001	1.03 (1.01 to 1.06)	<0.001
Sex		0.97†		0.84†		0.99†
Male	1.00*		1.00*		1.00*
Female	0.98 (0.92 to 1.04)	0.48	1.01 (0.98 to 1.04)	0.52	1.05 (1.03 to 1.07)	<0.001
Region		0.04†		<0.001†		<0.001†
England/North	1.03 (0.93 to 1.13)		1.21 (1.15 to 1.27)		1.08 (1.04 to 1.11)
England/Midlands	1.05 (0.95 to 1.16)		1.13 (1.08 to 1.27)		1.07 (1.04 to 1.11)
England/South	1.00*		1.00*		1.00*
England/London	0.83 (0.74 to 0.93)		0.84 (0.79 to 0.88)		0.81 (0.78 to 0.85)
Northern Ireland	1.64 (1.41 to 1.90)		1.20 (1.12 to 1.29)		1.46 (1.40 to 1.53)
Scotland	1.14 (1.03 to 1.26)		1.15 (1.09 to 1.21)		1.14 (1.11 to 1.18)
Wales	0.89 (0.79 to 0.99)	<0.001	0.80 (0.75 to 0.85)	<0.001	0.88 (0.85 to 0.91)	<0.001
High-risk condition		0.27†		<0.01†		0.04†
Chronic respiratory disease	1.00*		1.00*		1.00*
Chronic heart disease	0.86 (0.80 to 0.92)		0.68 (0.64 to 0.71)		0.57 (0.54 to 0.59)
Chronic neurological disease	0.75 (0.67 to 0.85)		0.69 (0.65 to 0.74)		0.61 (0.58 to 0.64)
Diabetes	1.55 (1.17 to 2.00)		1.78 (1.62 to 1.94)		1.81 (1.74 to 1.88)
Other high-risk condition‡	1.24 (1.08 to 1.40)	<0.001	1.16 (1.09 to 1.24)	<0.001	1.05 (1.01 to 1.09)	<0.001