Patient background
| Parameter | Overall (n=3340) | RCS-0 (n=2040) | RCS-1 (n=530) | RCS-2 (n=522) | RCS-3 (n=248) | p Value |
|---|---|---|---|---|---|---|
| Age, years | 65 (57–73) | 66 (57–74) | 64 (55–71) | 63 (55–71) | 66 (57–74) | <0.001 |
| Male, % | 76.9 | 75.8 | 80.0 | 77.6 | 78.2 | 0.197 |
| Onset to admission, hour | 2.4 (1.1–5.5) | 2.3 (1.0–5.0) | 2.3 (1.2–5.5) | 3.0 (1.5–6.7) | 3.0 (1.3–7.4) | <0.001 |
| Coronary risk factor | ||||||
| Diabetes, % | 31.6 | 31.0 | 31.7 | 32.3 | 34.6 | 0.705 |
| Hypertension, % | 58.1 | 59.1 | 58.4 | 53.5 | 59.5 | 0.147 |
| Dyslipidaemia, % | 44.2 | 40.8 | 50.4 | 47.6 | 52.1 | <0.001 |
| Smoking, % | 65.3 | 63.7 | 68.7 | 70.4 | 59.8 | 0.003 |
| Previous MI, % | 11.0 | 10.0 | 9.2 | 14.3 | 16.3 | <0.001 |
| Angina pectoris, % | 20.7 | 17.6 | 22.8 | 25.9 | 31.1 | <0.001 |
| KILLIP classification | 0.113 | |||||
| Class 1 | 82.0 | 80.9 | 83.2 | 84.8 | 82.8 | |
| Class 2 | 9.3 | 9.4 | 10.6 | 8.0 | 8.0 | |
| Class 3 | 2.5 | 2.4 | 2.1 | 2.9 | 2.5 | |
| Class 4 | 6.2 | 7.2 | 4.1 | 4.3 | 6.7 | |
| Laboratory data | ||||||
| Peak CPK, IU/L | 2957 (1637–5030) | 3225 (1722–5390) | 3074 (1895–4915) | 2514 (1449–4218) | 2277 (1093–4180) | <0.001 |
| CAG findings | ||||||
| Culprit vessel | <0.001 | |||||
| Left main trunk, % | 1.8 | 1.7 | 1.3 | 1.9 | 3.3 | |
| LAD, % | 44.0 | 42.7 | 48.3 | 45.2 | 42.7 | |
| Diagonal branch, % | 2.4 | 3.1 | 1.0 | 1.2 | 2.8 | |
| RCA, % | 41.5 | 40.1 | 43.5 | 44.8 | 41.9 | |
| LCx, % | 10.2 | 12.4 | 5.5 | 6.7 | 9.3 | |
| Graft, % | 0.1 | 0.0 | 0.4 | 0.2 | 0.0 | |
| Multivessel disease, % | 35.1 | 34.3 | 29.5 | 35.6 | 53.7 | <0.001 |
| Emergency PCI, % | 96.8 | 96.4 | 98.5 | 97.5 | 95.6 | 0.042 |
| Final TIMI 3, % | 85.8 | 84.9 | 85.4 | 87.8 | 89.6 | 0.127 |
| CABG, % | 1.7 | 1.6 | 1.2 | 1.7 | 3.7 | 0.064 |
| Medication at discharge | ||||||
| ACEI, % | 55.3 | 53.5 | 56.8 | 62.4 | 50.9 | 0.002 |
| ARB, % | 23.8 | 24.1 | 25.8 | 18.7 | 27.7 | 0.016 |
| β-Blocker, % | 48.7 | 49.0 | 50.3 | 45.0 | 51.3 | 0.271 |
| Ca-blocker, % | 16.8 | 17.9 | 15.0 | 15.3 | 15.6 | 0.297 |
| Statin, % | 41.8 | 40.9 | 42.0 | 42.0 | 47.3 | 0.334 |
| Diuretics, % | 29.0 | 29.7 | 28.8 | 26.9 | 28.6 | 0.664 |
Categorical variables are presented as percentage and continuous variables are presented as the median (25–75 percentiles).
ACEI, ACE inhibitor; ARB, angiotensin receptor blocker; CABG, coronary artery bypass graft; CAG, coronary angiography; CPK, creatine kinase; LAD, left anterior descending artery; LCx, left circumflex artery; PCI, percutaneous coronary intervention; RCA, right coronary artery; TIMI, thrombolysis in myocardial infarction.