Table 2

Extracted patient variables and results of univariate analysis

VariablesTotal
n=200 (% BC)
Blood culture+n=57 (% BC+)Blood culture–n=143 (% BC−)p Value
Demographic data of patientsMean±SD
Age64±19.071.3±14.961.5±19.80.0030*
n (%=/BC total (200))n (%=/BC+ (57))n (%=/BC− (143))
Female sex81 (40.5%)29 (51.0%)52 (36.4%)0.079
History of malignant diseases26 (13%)7 (12.3%)19 (13.2%)1.00
Recent surgical procedures within a month13 (6.5%)3 (5.3%)10 (7.0%)0.65
Use of immunosuppressive drugs12 (6.0%)5 (8.8%)7 (5.0%)0.33
HIV infection9 (4.5%)1 (1.8%)8 (5.6%)0.24
Patient admitted from health facility14 (7.0%)4 (7.0%)10 (7.0%)0.99
Preceding antimicrobial use within 2 weeks40 (20%)11 (19.3%)29 (20.3%)0.88
Medical devices
 Nasogastric tube3 (1.5%)2 (3.5%)1 (0.7%)0.14
 Indwelling urinary catheter5 (2.5%)3 (5.3%)2 (1.4%)0.11
 Central venous line15 (7.5%)8 (14.0%)7 (4.9%)0.037*
 Peripheral venous line24 (12%)9 (15.8%)15 (10.5%)0.34
 Other artificial devices17 (8.5%)5 (8.8%)12 (8.4%)0.93
Final diagnoses
 Infectious diseases1305773
 Pneumonia33 (16.5%)3 (5.3%)30 (21.0%)0.0058*
 Pyelonephritis18 (9%)12 (21.1%)6 (4.2%)0.0005*
 Cellulitis13 (6.5%)4 (7.0%)9 (6.3%)1.00
 Cholangitis/cholecystitis/liver abscess12 (6.0%)8 (14.0%)4 (2.8%)0.0053*
 Discitis/suppurative arthritis9 (4.5%)7 (12.3%)2 (1.4%)0.0025*
 Central line-associated bloodstream infection6 (3%)1 (1.7%)5 (3.4%)0.0077*
 Infective endocarditis6 (3%)6 (10.5%)0 (0.0%)NA
 Empyema/lung abscess5 (2.5%)0 (0.0%)5 (3.4%)NA
 Intra-abdominal infection5 (2.5%)0 (0.0%)5 (3.4%)NA
 Bacteraemia of unknown origin8 (4.0%)8 (14.0%)0 (0.0%)NA
 Other infectious diseases15 (7.5%)4 (7.0%)11 (7.6%)NA
 Non-infectious diseases45 (22.5%)0 (0.0%)45 (31.4%)NA
 Fever of unknown origin25 (12.5%)0 (0.0%)25 (17.4%)NA
Clinical and laboratory findingsMean±SD
 Axillary body temperature (°C)37.6±1.038.3±1.137.4±0.9<0.0001*
 Systolic blood pressure (mm Hg)120.1±18.7123.3±23.2118.9±16.50.34
 Diastolic blood pressure (mm Hg)65.0±10.967.4±14.064.1±9.40.16
 Pulse rate (/min)85.6±16.792.5±20.382.9±14.20.0022*
 White cell counts (×104/µL)10.5±5.811.9±5.010.1±6.00.0017*
 Neutrophils (%)78.0±13.284.8±9.375.3±13.6<0.0001*
 Lymphocytes (%)13.9±8.910.1±7.315.4±9.1<0.0001*
 Blood urea nitrogen (mg/gL)19.6±14.225.2±18.417.4±11.60.0004*
 Creatinine (mg/dL)0.90±0.801.09±1.230.82±0.530.039*
 Estimated glomerular filtration rate (mL/min)81.7±40.270.3±34.486.3±41.70.017*
 C reactive protein (mg/dL)8.0±7.19.0±7.97.7±6.90.49
 Body mass index (Kg/m2)21.6±3.921.9±4.021.6±3.90.56
 Haemoglobin A1c (%)5.8±0.95.9±0.95.9±0.90.77
 Albumin (g/dL)2.9±0.73.0±0.72.9±0.70.82
  • *p<0.05.

  • NA, not analysed.