Table 1

Predictive values of GMs, NPV and PPV, with respect to neurodevelopmental outcome between 18 and 24 months corrected age

Studies includedSample size (n)ParticipantsOutcome measure and age at outcomePreterm NPV (%)Post-term NPV (%)Preterm PPV (%)Post-term PPV (%)
Stahlmann et al63103Preterm infants <1500 gMotor outcome on the Griffiths Developmental Motor Scale at 20 months*84*89
Constantinou et al64102Preterm infants <1500 gNeurological examination and Bayley II scores at 18 months90*9029*41
Spittle et al65 94Preterm infants <30 weeksCognitive outcome on the Bayley III at 2 years†94 *96†14 *35
Language outcome on the Bayley III at 2 years†91 *93†14 *35
Motor outcome on the Bayley III at 2 years†100 *96†16 *35
  • *GMs at 3 months post-term, fidgety age.

  • †GMs at 1 month post-term, writhing age.

  • Bayley II, Bayley Scales of Infant and Toddler Development—Second Edition; Bayley III, Bayley Scales of Infant and Toddler Development—Third Edition; GM, General Movement; NPV, negative predictive value; PPV, positive predictive value.