Demographics and comorbidity of patients admitted with acute pancreatitis
| Patients coded as ICD10 K85 (AP) | Patients meeting definition of tAP | Patients meeting definition of sAP | Patients with sAP admitted to CC (a subset of sAP) | Patients with sAP not admitted to critical care (a subset of sAP that died without CC admission) | Patients not meeting definition of sAP (nsAP) | Comparison of nsAP versus sAP (statistically significant, p value; χ2 test 1 df, unless specified) | |
|---|---|---|---|---|---|---|---|
| Number of cases | |||||||
| (N, % total cases) | 3340 | 2053 (61.5) | 390 (11.7) | 368 (11.0) | 22 (0.7) | 1663 (49.8) | |
| (N, % tAP) | 390 (19.0) | 368 (17.9) | 22 (1.1) | 1663 (81.0) | |||
| (N, % sAP) | 368 (94.4) | 22 (5.6) | |||||
| Gender | |||||||
| (N female, % cases within category) | 1578 (47.2) | 1028 (50.1) | 183 (46.9) | 172 (46.7) | 11 (50) | 845 (50.8) | 0.167 |
| Age in years | |||||||
| Mean (SD) | 54.9 (18.5) | 55.8 (18.5) | 60.1 (18.0) | 59.2 (17.9) | 73.5 (13.5) | 54.8 (18.5) | <0.001 |
| Body mass index (N=1466) | |||||||
| Median (1st, 3rd quartile) | 26.7 (22.7, 31.6) | 27.5 (23.0, 32.3) | 28.4 (23.3, 33.1) | 28.4 (24.1, 33.1) | 22.1 (18.9, 30.7) | 27.3 (22.9, 32.0) | 0.227 |
| Proxies for lifestyle (from GP records) | |||||||
| (N for which this recorded, % total cases) | 1657 (49.6) | 1039 (50.6) | 195 (50.0) | 185 (50.3) | 10 (45.6) | 844 (50.8) | |
| Overweight | 238 (14.4) | 145 (14.0) | 47 (24.1) | 43 (23.2) | 4 (40.0) | 98 (11.6) | <0.001 |
| Prior/known alcohol overuse | 64 (3.9) | 33 (3.2) | 13 (6.7) | 12 (6.5) | 1 (10.0) | 20 (2.4) | 0.002 |
| Smoking | 615 (37.1) | 364 (35.0) | 85 (43.6) | 80 (43.2) | 5 (50.0) | 279 (33.1) | 0.006 |
| Aetiology of AP | |||||||
| (N aetiology recorded, %) | 3340 (100) | 2053 (100) | 390 (100.0) | 368 (100) | 22 (100) | 1663 (100) | |
| Gallstones (N, % of recorded) | 1482 (44.4) | 919 (44.8) | 171 (43.9) | 165 (44.8) | 6 (27.3) | 748 (45.0) | 0.686 |
| Alcohol+other non-gallstone* (N, % of recorded) | 1877 (55.6) | 1134 (55.3) | 219 (56.1) | 203 (55.2) | 16 (72.7) | 915 (55.0) | |
| Social deprivation quintile | |||||||
| Most deprived 1 | 1209 (36.4%) | 720 (35.3%) | 136 (35%) | 128 (34.9%) | 584 (35.4%) | Between groups | |
| (N, % within category) | |||||||
| 2 | 704 (21.2) | 412 (20.2) | 79 (20.3) | 72 (19.6) | 333 (20.2) | 0.971 (χ2 test 1 df trend) | |
| 3 | 543 (16.3) | 327 (16) | 66 (17) | 65 (17.7) | 261 (15.8) | ||
| 4 | 442 (13.3) | 283 (13.9) | 51 (13.1) | 48 (13.1) | 232 (14.0) | ||
| Most affluent 5 | 424 (12.8) | 299 (14.6) | 57 (14.7) | 54 (14.7) | 242 (14.6) | ||
| Duration of continuous inpatient stay, days | |||||||
| Median (1st, 3rd quartile) | 5 (3, 11) | 6 (3, 11) | 16 (9, 31) | 16 (10, 32) | 6 (2, 20) | 5 (3, 8) | <0.001 (Wilcoxon) |
Bold typeface signifies p<0.05.
*Exact proportion of alcohol diagnosis not possible for the entire cohort—see text for discussion.
AP, acute pancreatitis; CC, critical care; nsAP, not meeting definition of sAP; sAP, severe AP; tAP, true AP.