Healthcare prior to index AP admission
| Patients coded as ICD10 K85 (AP) | Patients meeting the definition of tAP | Patients meeting the definition of sAP | Patients with sAP admitted to CC (sAP-CC) | Patients with sAP not admitted to CC | Patients not meeting the definition of sAP (nsAP) | Comparison of nsAP versus sAP (statistically significant, p value; χ2 test 1 df, unless specified) | |
|---|---|---|---|---|---|---|---|
| Number of cases | |||||||
| (N, % total cases) | 3340 | 2053 (61.5) | 390 (11.7) | 368 (11.0) | 22 (0.7) | 1663 (49.8) | |
| Patients attending GP in year prior to admission | |||||||
| (N, % total cases) | 618 (18.5) | 317 (15.4) | 48 (12.3) | 42 (11.4) | 6 (27.3) | 269 (16.2) | |
| Number of GP visits in year prior to admission (GP attendees only) | |||||||
| Median (1st, 3rd quartile) | 5 (2, 11) | 5 (2, 10) | 7 (3, 13) | 5 (2, 12) | 12 (7, 18) | 5 (2, 9) | 0.075 (Mann-Whitney U-test) |
| A&E attendances in year prior to admission | |||||||
| Median (1st, 3rd quartile) | 1 (1, 3) | 1 (1, 2) | 1 (1, 2) | 1 (1, 2) | 2 (1, 4) | 1 (1, 2) | 0.745 (Mann-Whitney U-test) |
| Hospital inpatient stays in year prior to admission | |||||||
| Median (1st, 3rd quartile) | 1 (0, 2) | 1 (0, 3) | 1 (0, 2) | 1 (0, 2) | 2 (0, 4) | 1 (0, 2) | 0.119 (Mann-Whitney U-test) |
| Hospital outpatient visits in year prior to admission | |||||||
| Median (1st, 3rd quartile) | 1 (0, 3) | 1 (0, 3) | 1 (0, 3) | 1 (0, 3) | 1 (0, 2) | 1 (0, 3) | 0.202 (Mann-Whitney U-test) |
| Number of previous admissions with AP | |||||||
| Median (1st, 3rd quartile) | 2 (1, 3) | 1 (1, 2) | 1 (1, 2) | 1 (1, 3) | 1 (1, 2) | 1 (1, 3) | 0.045 (Mann-Whitney U-test) |
| Previous diagnoses or admissions | |||||||
| Acute pancreatitis | 968 (29.0) | 525 (25.6) | 72 (18.5) | 71 (19.3) | 1 (4.5) | 453 (27.2) | <0.001 |
| (N, % within category) | |||||||
| Gallstones | 628 (18.8) | 364 (17.7) | 61 (15.6) | 58 (15.8) | 2 (13.6) | 303 (18.2) | 0.230 |
| Alcohol-related psychiatric admission | 757 (22.7) | 338 (16.5) | 59 (15.1) | 56 (15.2) | 3 (13.6) | 279 (16.8) | 0.429 |
| Hypertension | 942 (28.2) | 595 (29.0) | 152 (39.0) | 143 (38.9) | 9 (40.9) | 443 (26.6) | <0.001 |
| Ischaemic heart disease | 539 (16.1) | 334 (16.3) | 102 (26.2) | 95 (25.8) | 7 (31.8) | 232 (14.0) | <0.001 |
| Myocardial infarction | 223 (6.7) | 146 (7.1) | 48 (12.3) | 45 (12.2) | 3 (13.6) | 98 (5.9) | <0.001 |
| Stroke or TIA | 226 (6.8) | 139 (6.8) | 41 (10.5) | 38 (10.3) | 3 (13.6) | 98 (5.9) | 0.001 |
| Hypercholesteraemia | 197 (5.9) | 125 (6.1) | 21 (5.4) | 21 (5.7) | 0 | 104 (6.3) | 0.518 |
| DM type 2 not on insulin | 471 (14.1) | 267 (13.0) | 79 (20.3) | 79 (21.5) | 0 | 188 (11.3) | <0.001 |
| DM type 2 treated with insulin | 57 (1.7) | 20 (1.0) | 6 (1.5) | 5 (1.4) | 1 (4.5) | 14 (0.8) | 0.208 |
| DM type 1 | 113 (3.4) | 45 (2.2) | 9 (2.3) | 9 (2.4) | 0 | 36 (2.2) | 0.862 |
| DM (unspecified) | 124 (3.7) | 66 (3.2) | 19 (4.9) | 18 (4.9 | 1 (4.5) | 47 (2.8) | 0.039 |
| Asthma | 345 (10.3) | 198 (9.6) | 45 (11.5) | 43 (11.7) | 2 (9.1) | 153 (9.2) | 0.159 |
| COPD | 313 (9.4) | 180 (8.8) | 47 (12.1) | 40 (10.9) | 7 (31.8) | 133 (8.0) | 0.011 |
| Chronic kidney disease | 247 (7.4) | 150 (7.3) | 49 (12.6) | 45 (12.2) | 4 (18.2) | 101 (6.1) | <0.001 |
| Acute kidney disease | 114 (3.4) | 62 (3.0) | 20 (5.1) | 16 (4.3) | 4 (18.2) | 42 (2.5) | 0.007 |
| Renal dialysis | 16 (0.5) | 7 (0.3) | 3 (0.8) | 3 (0.8) | 0 | 4 (0.2) | 0.107 |
| Chronic liver disease | 277 (8.3) | 119 (5.8) | 20 (5.1) | 19 (5.2) | 1 (4.5) | 99 (6.0) | 0.530 |
| Cystic fibrosis | 2 (0.1) | 1 (0.0) | 0 (0.0) | 0 (0.0) | 0 | 1 (0.1) | 0.628 |
| Abdominal trauma | 5 (0.1) | 1 (0.0) | 0 (0.0) | 0 (0.0) | 0 | 1 (0.1) | 0.628 |
AP, acute pancreatitis; CC, critical care; DM, diabetes mellitus; nsAP, not meeting definition of sAP; sAP, severe AP; tAP, true AP.