Average seasonal RSV-attributable burden of general practice episodes (CPRD) with any mention* of a respiratory disease diagnosis in the UK (1995–2009) by outcome and age
| Respiratory outcome | Age | N | Episodes/100 000 population (range) | Per cent of all events attributable to RSV† | RSV: influenza ratio‡ |
|---|---|---|---|---|---|
| Respiratory disease | <6 months | 47 844 | 14 441 (10 537–17 088) | 14.2 | 8.4:1 |
| 6–23 months | 130 758 | 12 936 (9209–14 934) | 10.8 | 4.4:1 | |
| 2–4 years | 161 540 | 7549 (4865–9636) | 10.2 | 2.4:1 | |
| 5–17 years | 110 016 | 1114 (632–1596) | 3.5 | 0.5:1 | |
| Acute upper respiratory disease | <6 months | 28 441 | 8585 (6420–10 411) | 12.9 | 7.2:1 |
| 6–23 months | 74 377 | 7358 (5485–8895) | 10.4 | 3.7:1 | |
| 2–4 years | 78 931 | 3689 (2521–4417) | 9.4 | 1.9:1 | |
| 5–17 years | 48 437 | 491 (277–705) | 3.0 | 0.4:1 | |
| Bronchitis/bronchiolitis | <6 months | 24 853 | 7502 (5094–9049) | 41.5 | 18.1:1 |
| 6–23 months | 57 096 | 5649 (3942–6598) | 29.7 | 16.1:1 | |
| 2–4 years | 43 685 | 2042 (1398–2440) | 24.6 | 7.4:1 | |
| 5–17 years | 23 939 | 242 (162–298) | 8.9 | 0.9:1 | |
| Pneumonia and influenza | <6 months | 458 | 138 (71–214) | 25.9 | 1.3:1 |
| 6–23 months | 1680 | 166 (109–208) | 19.6 | 0.6:1 | |
| 2–4 years | 2233 | 104 (63–141) | 15.4 | 0.3:1 | |
| 5–17 years | 2375 | 24 (7–49) | 4.6 | 0.1:1 | |
| Otitis media | <6 months | 1533 | 463 (203–783) | 9.1 | 2.5:1 |
| 6–23 months | 23 426 | 2318 (1295–3359) | 8.9 | 3.0:1 | |
| 2–4 years | 56 201 | 2626 (1437–3870) | 13.0 | 3.4:1 | |
| 5–17 years | 44 318 | 449 (226–702) | 6.3 | 1.3:1 | |
| Antibiotic prescription | <6 months | 27 592 | 8328 (5547–10 265) | 19.7 | 9.8:1 |
| 6–23 months | 120 447 | 11 916 (8432–13 684) | 14.6 | 6.9:1 | |
| 2–4 years | 160 368 | 7495 (5084–9051) | 13.6 | 3.8:1 | |
| 5–17 years | 107 726 | 1091 (686–1427) | 4.2 | 0.8 |
*For CPRD data, there is no ordered listing or ranking of diagnostic codes. N=average seasonal number of specified RSV-attributable events for each outcome.
†Per cent of RSV-attributable events among all events due to outcome.
‡Ratio of proportions/100 000 RSV/(influenza A+B).
Range=range of estimates per season.
CPRD, clinical practice research datalink; RSV, respiratory syncytial virus.