Table 1

Trends in market share by prescription volume of antineoplastic agents for eye cancer in Taiwan by drug class

Number of prescriptions
2009201020112012
Drug classDrug namesVolume(%)Volume(%)Volume(%)Volume(%)
All antineoplastic agents707100.00832100.00741100.00634100.00
Targeted therapies111.56414.93324.326410.09
 Monoclonal antibodiesRituximab111.56121.4450.6781.26
 Protein kinase inhibitorsGefitinib, erlotinib, sunitinib00.00293.49233.10528.20
 Other targeted therapiesBortezomib00.0000.0040.5440.63
Alkylating agents18225.7425530.6520026.9918128.55
 Nitrogen mustard analoguesCyclophosphamide, chlorambucil, melphalan, ifosfamide14620.6521625.9614719.8413320.98
 NitrosoureasCarmustine00.0000.0030.4030.47
 Other alkylating agentsTemozolomide, dacarbazine365.09394.69506.75457.10
Antimetabolites15421.7811914.3012416.7314623.03
 Folic acid analoguesMethotrexate, pemetrexed425.94263.13395.26446.94
 Pyrimidine analoguesCytarabine, fluorouracil, tegafur, gemcitabine, tegafur+uracil11215.849311.188511.4710216.09
Plant alkaloids and other natural products12517.6814817.7914018.899014.20
 Vinca alkaloids and analoguesVinblastine, vincristine, vinorelbine628.779611.54719.58619.62
 Podophyllotoxin derivativesEtoposide547.64526.25638.50294.57
 TaxanesPaclitaxel, docetaxel91.2700.0060.8100.00
Cytotoxic antibiotics and related substances14620.6517320.7911215.117111.20
 ActinomycinesDactinomycin,50.7100.0000.0000.00
 Anthracyclines and related substancesDoxorubicin, epirubicin, idarubicin436.08667.93516.88243.79
 Other cytotoxic antibioticsBleomycin, mitomycin C9813.8610712.86618.23477.41
Other agents8912.599611.5413317.958212.93
 Platinum compoundsCisplatin, carboplatin8912.599611.5413317.958212.93