Cox proportional hazards regression of all-cause mortality for serum LDH in those with and without MetS
| Models* | MetS | Non-MetS | ||||
|---|---|---|---|---|---|---|
| Serum LDH level tertiles | HR (95% CI) | p Value | Serum LDH level tertiles | HR (95% CI) | p Value | |
| Model 1 | T2 vs T1 T3 vs T1 | 1.205 (1.007 to 1.441) 1.572 (1.315 to 1.881) | 0.041 <0.001 | T2 vs T1 T3 vs T1 | 1.557 (1.286 to 1.886) 2.133 (1.774 to 2.564) | <0.001 <0.001 |
| Model 2 | T2 vs T1 T3 vs T1 | 0.980 (0.819 to 1.174) 1.220 (1.017 to 1.463) | 0.827 0.033 | T2 vs T1 T3 vs T1 | 1.122 (0.925 to 1.361) 1.070 (0.884 to 1.295) | 0.242 0.486 |
| Model 3 | T2 vs T1 T3 vs T1 | 1.006 (0.837 to 1.210) 1.273 (1.049 to 1.547) | 0.947 0.015 | T2 vs T1 T3 vs T1 | 1.191 (0.980 to 1.448) 1.213 (0.992 to 1.484) | 0.079 0.060 |
*Adjusted covariates.
Model 1=unadjusted.
Model 2=adjustment for age, race, sex and BMI.
Model 3=model 2+serum CRP, serum total bilirubin, serum creatinine, serum aspartate transaminase, serum uric acid, smoking, CVD, cancer.
BMI, body mass index; CRP, C reactive protein; CVD, cardiovascular disease; LDH, lactate dehydrogenase; MetS, metabolic syndrome.