Table 1

Prevalence of cytological abnormalities, unsatisfactory smears and histologically confirmed high-grade cervical intraepithelial neoplasia by age group

Age20–2425–2930–3435–3940–4445–4950–5455–5960+Total
N participants (%)629 (11.8)486 (9.1)513 (9.6)577 (10.8)691 (13.0)853 (16.0)831 (15.6)593 (11.1)145 (2.7)5318 (100)
Cytology
 BL (%)46 (0.7)17 (3.5)15 (2.9)12 (2.0)10 (1.4)17 (2.0)5 (0.6)3 (0.5)0 (0.0)125 (2.3)
 LG (%)31 (0.5)13 (2.7)10 (1.9)4 (0.6)8 (1.2)4 (0.4)1 (0.1)3 (0.5)0 (0.0)74 (1.4)
 HG* (%)10 (1.5)17 (3.4)12 (2.3)9 (1.5)5 (0.7)4 (0.4)1 (0.1)3 (0.5)1 (0.6)62 (1.1)
 Unsatisfactory (%)†3 (0.4)9 (1.8)8 (1.5)7 (1.2)14 (2.0)17 (1.9)25 (3.0)30 (5.0)10 (6.8)123 (2.3)
HistologyN (%)
 Cancer0020100003 (0.05)
 CIN31420‡1085712168 (1.2)
 CIN21319986400059 (1.1)§
 CIN2+ (%)27 (4.3%)39 (8%)21 (4.1%)16 (2.8%)12 (1.7%)11 (1.3%)1 (0.1%)2 (0.3%)1 (0.7%)130 (2.4)
  • In total, 222 colposcopies were performed (137 due to abnormal cytology and 85 due to PaVDaG protocol).

  • *Includes glandular abnormalities (n=6).

  • †Linear trend in unsatisfactory cytology samples with age p<0.001.

  • ‡Includes GCIN3 (n=2).

  • §Two of these CIN2 cases had failed cervical HPV tests, so they feature only in the sensitivity/specificity calculations for cytology—as they were in the BA/LG and HG groups of patients

  • BL, borderline abnormality; CIN2+, cervical intraepithelial neoplasia (grade 2 or 3 or cancer); GCIN, glandular cervical intraepithelial neoplasia; HG, high-grade dyskaryosis; HPV, human papillomavirus; LG, low-grade dyskaryosis; PaVDaG, Papillomavirus Dumfries and Galloway.