Participant timeline for RCT
| Day | Enrolment and randomisation | Background and clinical information | Colistin levels | Clinical follow-up | Outcome data | Rectal surveillance swabs | Blood cultures if febrile | Other microbiological sampling* |
|---|---|---|---|---|---|---|---|---|
| 1 | X | X | X | X | X | X | ||
| 2 | X | X | X | |||||
| 5 | X | X | ||||||
| 7 | X | X | X | X | X | |||
| 9 | X | |||||||
| 10 | X | |||||||
| 14 | X | X | X | X | ||||
| 21 | X | |||||||
| 28 | X | X | X |
*Index culture on day 1 (randomisation); Sputum culture for patients with HAP/VAP and urine culture for patients with urosepsis on day 7.
HAP, hospital-acquired pneumonia; RCT, randomised controlled trial; VAP, ventilator-associated pneumonia.