Table 4

Factors associated with pharmacy and polypharmacy, multinomial logistic regression (n=658)

Polypharmacy categories
Polypharmacy (5–9 medicines)Excessive polypharmacy (10+ medicines)
CharacteristicOR (95% CI)p ValueOR (95% CI)p Value
Gender
 Male1.001.00
 Female0.95 (0.62–1.45)0.810.93 (0.55–1.56)0.78
Age (years)
 40–491.001.00
 50–641.12 (0.71–1.77)0.640.75 (0.43–1.34)0.33
 65+1.63 (0.87–3.07)0.131.79 (0.87–3.68)0.12
Level of ID
 Mild1.001.00
 Moderate1.34 (0.79–2.300.770.77 (0.39–1.510.45
 Severe/profound4.06 (2.08–7.91<0.0011.38 (0.62–3.100.43
Residence
 Independent/community group home1.001.00
 Residential institution2.08 (1.33–3.25)0.0016.90 (3.88–12.25)<0.001
Conditions
Mental health
 No1.001.00
 Yes3.98 (2.59–6.11)<0.0016.05 (3.55–10.31)<0.001
Neurological
 No1.001.00
 Yes3.67 (2.32–5.80)<0.0016.08 (3.51–10.53)<0.001
Gastrointestinal disease
 No1.001.00
 Yes1.10 (0.66–1.84)0.732.66 (1.51–4.67)0.001
Joint disease
 No1.001.00
 Yes1.52 (0.89–2.58)0.121.33 (0.71–2.51)0.37
Endocrine disease
 No1.001.00
 Yes2.06 (1.23–3.47)0.0063.69 (2.00–6.80)<0.001
Eye condition
 No1.001.00
 Yes0.67 (0.44–1.00)0.050.68 (0.39–1.17)0.17
Hypertension
 No1.001.00
 Yes3.09 (1.65–5.80)<0.0013.68 (1.78–7.63)<0.001
Heart disease
 No1.001.00
 Yes1.20 (0.63–2.31)0.581.51 (0.71–3.22)0.28
  • Reference category=no polypharmacy (0–4 medicines), p<0.05 is significant, all significant factors in bold.

  • Cox and Snell r2=0.39 Nagelkerke r2=0.44.