Table 3

Frequencies, percentages and crude ORs of adverse reactions with respect to sex, BMI, ethnicity and age category stratified by cycloplegic eye drop treatment

	C+C*				C+T†
	n	n (%) AR	Crude OR 95% CI	p Value	n	n (%) AR	Crude OR 95% CI	p Value
	408	42 (10.3)			504	24 (4.8)
Sex	408	42			504	24
Male	207	25 (12.1)	1‡		260	12 (4.6)	1‡
Female	201	17 (8.5)	0.7 (0.4 to1.3)	0.23	244	12 (4.9)	0.9 (0.4 to 2.1)	0.87
BMI category	408	42			504	24
Low BMI	18	13 (72.2)	24.5 (8.1 to 73.8)	<0.001	29	10 (34.5)	14.3 (5.6 to 36.8)	<0.001
Normal BMI	292	28 (9.6)	1‡		366	13 (3.6)	1‡
High BMI	98	1 (1.0)	0.1 (0.01 to 0.7)	0.02	109	1 (0.9)	0.3 (0.03 to 1.9)	0.19
Ethnic main group	359	39 (10.9)			437	21 (4.9)
Dutch	110	13 (11.8)	1‡		137	6 (4.4)	1‡
Moroccan	81	10 (12.3)	1.1 (0.4 to 2.5)	0.91	107	5 (4.7)	1.1 (0.3 to 3.6)	0.91
Turkey	71	5 (7.0)	0.6 (0.2 to 1.7)	0.30	86	4 (4.7)	1.1 (0.3 to 3.9)	0.92
Indian subcontintent	68	10 (14.7)	1.3 (0.5 to 3.1)	0.58	73	5 (6.8)	1.6 (0.5 to 5.5)	0.45
Negro	29	1 (3.4)	0.3 (0.03 to 2.1)	0.21	34	1 (2.9)	0.7 (0.08 to 5.7)	0.71
Other	49	3 (6.1)	0.5 (0.1 to 1.8)	0.28	67	3 (4.5)	1.0 (0.3 to 4.2)	0.97
Age category (year)	408	42			504	24
3–6	163	34 (20.9)	10.2 (3.5 to 29.4)	<0.001	200	15 (7.5)	2.5 (0.95 to 6.6)	0.06
7–10	158	4 (2.5)	1‡		191	6 (3.1)	1‡
11–14	87	4 (4.6)	1.9 (0.5 to 7.6)	0.39	113	3 (2.7)	0.8 (0.2 to 3.4)	0.81
Age category 3–6	163	34			200	15
Low BMI	13	11 (84.6)			14	4 (28.6)
Normal BMI	125	22 (17.6)			157	10 (6.4)
High BMI	25	1 (4.0)			29	1 (3.4)
Age category 7–10	158	4			191	6
Low BMI	3	1 (33.3)			9	3 (33.3)
Normal BMI	104	3 (2.9)			129	3 (2.3)
High BMI	51	0			53	0
Age category 11–14	87	4			113	3
Low BMI	2	1 (50.0)			6	3 (50.0)
Normal BMI	63	3 (4.8)			80	0
High BMI	22	0			27	0

*C+C: Two drops of cyclopentolate 1%.
†C+T: One drop of cyclopentolate 1% followed by one drop of tropicamide 1%.
‡1: Reference group.
AR, Adverse reactions; BMI, body mass index.