Table 3

Frequencies, percentages and crude ORs of adverse reactions with respect to sex, BMI, ethnicity and age category stratified by cycloplegic eye drop treatment

C+C*C+T†
nn (%) ARCrude OR 95% CIp Valuenn (%) ARCrude OR 95% CIp Value
40842 (10.3)50424 (4.8)
Sex4084250424
Male20725 (12.1)1‡26012 (4.6)1‡
Female20117 (8.5)0.7 (0.4 to1.3)0.2324412 (4.9)0.9 (0.4 to 2.1)0.87
BMI category4084250424
 Low BMI1813 (72.2)24.5 (8.1 to 73.8)<0.0012910 (34.5)14.3 (5.6 to 36.8)<0.001
 Normal BMI29228 (9.6)1‡36613 (3.6)1‡
 High BMI981 (1.0)0.1 (0.01 to 0.7)0.021091 (0.9)0.3 (0.03 to 1.9)0.19
Ethnic main group35939 (10.9)43721 (4.9)
 Dutch11013 (11.8)1‡1376 (4.4)1‡
 Moroccan8110 (12.3)1.1 (0.4 to 2.5)0.911075 (4.7)1.1 (0.3 to 3.6)0.91
 Turkey715 (7.0)0.6 (0.2 to 1.7)0.30864 (4.7)1.1 (0.3 to 3.9)0.92
 Indian subcontintent6810 (14.7)1.3 (0.5 to 3.1)0.58735 (6.8)1.6 (0.5 to 5.5)0.45
 Negro291 (3.4)0.3 (0.03 to 2.1)0.21341 (2.9)0.7 (0.08 to 5.7)0.71
 Other493 (6.1)0.5 (0.1 to 1.8)0.28673 (4.5)1.0 (0.3 to 4.2)0.97
Age category (year)4084250424
 3–616334 (20.9)10.2 (3.5 to 29.4)<0.00120015 (7.5)2.5 (0.95 to 6.6)0.06
 7–101584 (2.5)1‡1916 (3.1)1‡
 11–14874 (4.6)1.9 (0.5 to 7.6)0.391133 (2.7)0.8 (0.2 to 3.4)0.81
Age category 3–61633420015
 Low BMI1311 (84.6)144 (28.6)
 Normal BMI12522 (17.6)15710 (6.4)
 High BMI251 (4.0)291 (3.4)
Age category 7–1015841916
 Low BMI31 (33.3)93 (33.3)
 Normal BMI1043 (2.9)1293 (2.3)
 High BMI510530
Age category 11–148741133
 Low BMI21 (50.0)63 (50.0)
 Normal BMI633 (4.8)800
 High BMI220270
  • *C+C: Two drops of cyclopentolate 1%.

  • †C+T: One drop of cyclopentolate 1% followed by one drop of tropicamide 1%.

  • ‡1: Reference group.

  • AR, Adverse reactions; BMI, body mass index.