Prevalence, number and gender for all individuals with severe mental illness (SMI) diagnosis*, mean years with first and latest SMI diagnosis and prescribed medications†, over time
| 2000/2001 | 2001/2002 | 2002/2003 | 2003/2004 | 2004/2005 | 2005/2006 | 2006/2007 | 2007/2008 | 2008/2009 | 2009/2010 | 2010/2011 | 2011/2012 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prevalence of individuals with SMI diagnosis | ||||||||||||
| Schizophrenia | 0.11 | 0.11 | 0.12 | 0.12 | 0.13 | 0.13 | 0.13 | 0.14 | 0.13 | 0.14 | 0.14 | 0.14 |
| Bipolar disorder | 0.13 | 0.13 | 0.14 | 0.15 | 0.15 | 0.16 | 0.16 | 0.17 | 0.17 | 0.18 | 0.18 | 0.19 |
| Unspecified/other affective psychosis | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 |
| Other types of psychosis | 0.18 | 0.18 | 0.19 | 0.2 | 0.2 | 0.2 | 0.2 | 0.21 | 0.21 | 0.21 | 0.22 | 0.23 |
| Number of individuals with SMI diagnosis (not exclusively) | ||||||||||||
| Schizophrenia | 4098 | 4674 | 5268 | 5842 | 6339 | 6727 | 7059 | 7281 | 7296 | 7323 | 7205 | 7029 |
| Bipolar disorder | 4906 | 5613 | 6352 | 7083 | 7784 | 8259 | 8701 | 9055 | 9332 | 9715 | 9727 | 9496 |
| Unspecified/other affective psychosis | 1938 | 2150 | 2392 | 2573 | 2839 | 2999 | 3255 | 3398 | 3551 | 3690 | 3696 | 3605 |
| Other SMI | 6862 | 7691 | 8764 | 9551 | 10 226 | 10 628 | 10 857 | 11 226 | 11 484 | 11 623 | 11 665 | 11 631 |
| Percentage of male individuals with SMI diagnoses | ||||||||||||
| Schizophrenia | 54.86 | 55.63 | 57.52 | 58.37 | 58.98 | 59.86 | 60.41 | 60.86 | 60.68 | 61.35 | 61.5 | 61.79 |
| Bipolar disorder | 39.52 | 39.66 | 39.97 | 39.93 | 39.92 | 39.77 | 39.46 | 39.72 | 39.71 | 39.66 | 39.8 | 39.49 |
| Unspecified/other affective psychosis | 32.04 | 33.26 | 34.36 | 35.29 | 35.51 | 35.45 | 36.65 | 37.7 | 37.37 | 37.32 | 37.28 | 37.14 |
| Other types of psychosis | 48.32 | 49.25 | 49.55 | 50.38 | 50.76 | 51.4 | 51.39 | 51.88 | 51.68 | 52.34 | 52.2 | 52.51 |
| Mean number of years with SMI diagnosis (SD) | ||||||||||||
| First SMI diagnosis | 11.7 (11.5) | 11.8 (11.6) | 11.8 (11.6) | 11.8 (11.6) | 11.8 (11.6) | 12.1 (11.7) | 12.2 (11.7) | 12.3 (11.6) | 12.6 (11.7) | 12.8 (11.7) | 13.0 (11.7) | 13.2 (11.8) |
| Latest SMI diagnosis | 9.1 (11.3) | 9.2 (11.3) | 9.4 (11.2) | 9.5 (11.2) | 9.6 (11.1) | 9.9 (11.1) | 10.1 (11.0) | 10.3 (10.9) | 10.6 (10.9) | 10.9 (10.9) | 11.3 (11.0) | 11.5 (11.0) |
| Antipsychotics‡ | ||||||||||||
| First generation (conventional) | 20.26 | 20.11 | 17.64 | 15.31 | 14.79 | 13.84 | 12.71 | 11.94 | 11.03 | 10.12 | 9.39 | 8.78 |
| Second generation (atypical) | 18.1 | 23.03 | 27.12 | 30.68 | 33.33 | 35.77 | 37.75 | 38.8 | 39.82 | 40.57 | 41.77 | 43.02 |
| Depot | 5.95 | 5.65 | 5.15 | 4.69 | 4.45 | 4.13 | 3.83 | 3.65 | 3.5 | 3.5 | 3.32 | 3.23 |
| Antidepressants‡ | ||||||||||||
| Tricyclic | 14.03 | 12.94 | 12.23 | 11.81 | 11.17 | 10.32 | 9.81 | 9.4 | 9.28 | 9.19 | 9.32 | 9.21 |
| Selective serotonin reuptake inhibitors | 18.13 | 19.65 | 20.27 | 20.41 | 20.92 | 21.16 | 22.58 | 22.95 | 23.8 | 24.38 | 25.23 | 25.75 |
| Other antidepressants§ | 6.87 | 8.7 | 10.05 | 11.18 | 12.21 | 12.3 | 12.67 | 13.17 | 13.31 | 13.83 | 14.5 | 14.96 |
*In instances where an individual received more than one SMI diagnostic subcategory diagnoses during the study period, the patient was assigned to the last diagnostic category received, since it was likely to be based on a greater knowledge of the individual’s clinical history.
†Patients were considered to be associated with a medication group if they received at least one prescription of a relevant drug within the respective year.
‡Organised by chapters in British National Formulary (BNF) 67 (March 2014).
§Not listed in BNF 67 (March 2014).