Cost and effectiveness assessment
| Panel A: Effectiveness assessment (30-day avoided mortality) | ||||||
|---|---|---|---|---|---|---|
| Pre-STEMI network | Post-STEMI network | |||||
| 30-Day mortality (%) (a) | Reperfusion strategy distribution (%) (b) | Weighted mortality (%) (c)=(a)*(b) | 30-Day mortality (%) (a) | Reperfusion strategy distribution (%) (b) | Weighted mortality (%) (c)=(a)*(b) | |
| Primary PCI | 7.7 | 31 | 2.39 | 5.6 | 88.5 | 4.96 |
| Fibrinolysis | 10.5 | 37 | 3.88 | 3.6 | 3.9 | 0.14 |
| Rescue PCI | 15.1 | 11 | 1.66 | 13.6 | 3 | 0.41 |
| No reperfusion | 13.4 | 21 | 2.81 | 15.1 | 4.6 | 0.69 |
| Protocol Effectiveness* | 89.2 | 93.8 | ||||
| Panel B: Costs assessment | ||||||
|---|---|---|---|---|---|---|
| Pre-STEMI network | Post-STEMI network | |||||
| Mean costs (€) (a) | Reperfusion strategy distribution (%) (b) | Weighted costs (€) (c)=(a)*(b) | Mean costs (€) (a) | Reperfusion strategy distribution (%) (b) | Weighted costs (€) (c)=(a)*(b) | |
| Primary PCI | 8306 | 31 | 2572.9 | 7874 | 88.5 | 6968.5 |
| Fibrinolysis | 5956 | 37 | 2203.7 | 5956 | 3.9 | 232.3 |
| Rescue PCI | 10 806 | 11 | 1188.7 | 10 086 | 3 | 302.6 |
| No reperfusion | 8160 | 21 | 1713.6 | 8160 | 4.6 | 375.4 |
| Protocol Cost (€) | 7680.8 | 7878.7 | ||||
*Protocol effectiveness=100-(Σ weighted mortality).
PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction.