Factors associated with the rate of decline on MMSE
| Coefficient | p Value | |
|---|---|---|
| Follow-up time in years | −3.20 (−3.69, −2.7) | <0.0005 |
| Diagnosis | 1.63 (0, 3.27) | 0.050 |
| Sex | 0.41 (−1.01, 1.83) | 0.571 |
| Age in years | 0.04 (−0.05, 0.13) | 0.402 |
| CIRS scores at baseline | −0.01 (−0.3, 0.29) | 0.957 |
| Duration of symptoms before baseline in years | −0.10 (−0.41, 0.21) | 0.524 |
| MMSE scores at baseline | 0.83 (0.58, 1.08) | <0.0005 |
| CDR at baseline | −2.48 (−4.16, −0.8) | 0.004 |
| Diagnosis x year | −1.24 (−2.15, −0.32) | 0.008 |
Linear mixed effects analysis, covariate adjusted.
CDR, Clinical Dementia Rating; CIRS, Cumulative illness rating scale; ; MMSE, Mini-Mental State Examination.