Adults (≥18 years);

Idiopathic overactive bladder, with/without urinary incontinence;

Conditions described as:

• Refractory detrusor overactivity;

• Idiopathic urge urinary incontinence;

• Non-neurogenic urge urinary incontinence.

Patients with overactive bladder and urinary incontinence with a known cause (eg, surgery, pregnancy, benign prostatic hyperplasia, bladder outlet obstruction;

Neurogenic overactive bladder;

Stress urinary incontinence;

Bladder oversensitivity;

Bladder hypersensitivity;

Mixed populations where results not reported separately for idiopathic overactive bladder subgroup.

OnabotulinumtoxinA (all doses);

Mirabegron (all doses).

OnabotulinumtoxinA;

Mirabegron;

Sacral nerve stimulation;

Percutaneous tibial nerve stimulation;

Anticholinergics (including solifenacin/tolterone);

Sham treatments;

Placebo;

Best supportive care.

Episodes of urinary incontinence:

• Change in number of episodes;

• Proportion of patients who achieve ≥50% reduction in number of episodes

Urinary frequency;

Urgency;

Nocturia.

Randomised controlled trials;

Cross-over randomised controlled trials if data reported at cross-over.

Retrospective studies;

Non-English reports;

Abstracts/conference presentations.