Summary of results for prehabilitation versus no prehabilitation
| Outcomes | Studies, (n) | Patients, (n) | Heterogeneity test p value | I2 (%) | WMD and 95% CI |
|---|---|---|---|---|---|
| Pain at 4 weeks or less | 4 | 213 | 0.08 | 55 | −6.1 (−10.6 to −1.6)* |
| Pain at 6–8 weeks | 5 | 488 | 0.31 | 16 | −1.4 (−5.5 to +2.6) |
| Pain at 12 weeks | 10 | 806 | 0.05 | 46 | −2.9 (−6.2 to +0.3) |
| Pain at 24 weeks | 3 | 247 | 0.22 | 33 | −2.5 (−5.6 to +0.6) |
| Pain at 1 year or more | 1 | 109 | NA | NA | −2.0 (−7.5 to +3.5) |
| Function at 4 weeks or less | 5 | 257 | <0.001 | 79 | −3.6 (−7.7 to +0.5) |
| Function at 6–8 weeks | 5 | 488 | 0.21 | 31 | −3.9 (−7.6 to −0.3)* |
| Function at 12 weeks | 12 | 836 | <0.001 | 69 | −4.0 (−7.5 to −0.5)* |
| Function at 24 weeks | 5 | 345 | <0.001 | 89 | −0.5 (−5.8 to +4.7) |
| Function at 1 year or more | 6 | 296 | 0.99 | 0 | −0.6 (−2.6 to +145) |
| First days of climbing stairs (days) | 2 | 99 | 0.44 | 0 | −1.4 (−1.9 to −0.8)* |
| First days of walking (days) | 2 | 99 | 0.24 | 29 | −0.2 (−0.4 to +0.002) |
| First days of use of toilet (days) | 2 | 99 | 0.87 | 0 | −0.9 (−1.3 to −0.5)* |
| First days of use of chair (days) | 2 | 99 | 0.50 | 0 | −1.2 (−1.7 to −0.8)* |
| SF-36 PCS at 6 weeks | 1 | 19 | NA | NA | 2.7 (−9.4 to +14.7) |
| SF-36 PCS at 12 weeks | 3 | 149 | 0.13 | 50 | −0.3 (−5.4 to +4.7) |
| SF-36 PCS at 24 weeks | 1 | 109 | NA | NA | 0.0 (−3.4 to +3.4) |
| SF-36 PCS at 1 year | 1 | 109 | NA | NA | −3.0 (−6.4 to +0.4) |
| SF-36 MCS at 6 weeks | 1 | 17 | NA | NA | −3.4 (−19.9 to +13.0) |
| SF-36 MCS at 12 weeks | 3 | 149 | 0.72 | 0 | −0.4 (−3.7 to +2.9) |
| SF-36 MCS at 24 weeks | 1 | 109 | NA | NA | −1.0 (−4.9 to +2.9) |
| SF-36 MCS at 1 year | 1 | 109 | NA | NA | −2.0 (−5.1 to +1.1) |
| Length of stay (days) | 7 | 507 | 0.68 | 0 | −0.3 (−0.8 to + 0.1) |
| Total cost (Canadian dollars) | 2 | 242 | 0.99 | 0 | +5 (−384 to +393) |
Pain and function scores were converted to WOMAC (Western Ontario and McMaster Universities osteoarthritis index) 0–100 subscales, and high score indicates more pain or dysfunction.
*p<0.05.
MCS, mental component summary; NA, not applicable; PCS, physical component summary; WMD, weighted mean difference.