RT Journal Article SR Electronic T1 Education Against Tobacco (EAT): a quasi-experimental prospective evaluation of a multinational medical-student-delivered smoking prevention programme for secondary schools in Germany JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e008093 DO 10.1136/bmjopen-2015-008093 VO 5 IS 9 A1 Titus J Brinker A1 Sabine Stamm-Balderjahn A1 Werner Seeger A1 Doris Klingelhöfer A1 David A Groneberg YR 2015 UL http://bmjopen.bmj.com/content/5/9/e008093.abstract AB Objectives To evaluate the multinational medical-student-delivered tobacco prevention programme for secondary schools for its effectiveness to reduce the smoking prevalence among adolescents aged 11–15 years in Germany at half year follow-up.Setting We used a prospective quasi-experimental study design with measurements at baseline (t1) and 6 months postintervention (t2) to investigate an intervention in 8 German secondary schools. The participants were split into intervention and control classes in the same schools and grades.Participants A total of 1474 eligible participants of both genders at the age of 11–15 years were involved within the survey for baseline assessment of which 1200 completed the questionnaire at 6-month follow-up (=longitudinal sample). The schools participated voluntarily. The inclusion criteria were age (10–15 years), grade (6–8) and school type (regular secondary schools).Intervention Two 60 min school-based modules delivered by medical students.Primary and secondary outcome measures The primary end point was the difference from t1 to t2 of the smoking prevalence in the control group versus the difference from t1 to t2 in the intervention group (difference of differences approach). The percentage of former smokers and new smokers in the two groups were studied as secondary outcome measures.Results In the control group, the percentage of students who claimed to be smokers doubled from 4.2% (t1) to 8.1% (t2), whereas it remained almost the same in the intervention group (7.1% (t1) to 7.4% (t2); p=0.01). The likelihood of quitting smoking was almost six times higher in the intervention group (total of 67 smokers at t1; 27 (4.6%) and 7 (1.1%) in the control group; OR 5.63; 95% CI 2.01 to 15.79; p<0.01). However, no primary preventive effect was found.Conclusions We report a significant secondary preventive (smoking cessation) effect at 6-month follow-up. Long-term evaluation is planned.