PT  - JOURNAL ARTICLE
AU  - Christin Henein
AU  - Clarissa E H Fang
AU  - Desta Bokre
AU  - Maaz Khan
AU  - Ahmed Adan
AU  - Yann Bouremel
AU  - Mayank A Nanavaty
TI  - Optical aberrations following implantation of multifocal intraocular lenses: a systematic review and meta-analysis protocol
AID  - 10.1136/bmjopen-2021-059350
DP  - 2022 Aug 01
TA  - BMJ Open
PG  - e059350
VI  - 12
IP  - 8
4099  - http://bmjopen.bmj.com/content/12/8/e059350.short
4100  - http://bmjopen.bmj.com/content/12/8/e059350.full
SO  - BMJ Open2022 Aug 01; 12
AB  - Introduction Multifocal intraocular lens (IOLs) are used to restore vision at different focal distances. The technology of multifocal IOLs is continually advancing. Optical aberrations a property of lenses that causes spreading of light over a region resulting in a blurred or distorted image. This study aims to systematically review investigator measured and patient reported optical aberrations following implantation of multifocal IOLs during phacoemulsification surgery to treat presbyopia in adults.Methods and analysis We will conduct an electronic database search for randomised controlled trials, prospective non-randomised studies, observational studies in Ovid MEDLINE, Ovid EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, Scopus and ClinicalTrials.gov in March 2021. Eligibility criteria will include quantitative articles written in English and containing data on optical aberrations. Two independent reviewers will screen titles and abstracts and extract data from full texts, reporting outcomes according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data extraction of key characteristics will be completed using customised forms. Methodological quality will be assessed using Cochrane Handbook 6.2.Ethics and dissemination Ethics approval is not required for this review, as it will only include published data. Findings will be published in a peer-reviewed journal and disseminated across ophthalmic networks. We anticipate that the findings of this work will be of interest to multiple stakeholders: people who have undergone cataract surgery, eye health professionals, ophthalmic surgeons, device manufacturers and policy-makers. It will also inform researchers to where there are gaps in evidence and identify areas for future research.PROSPERO registration number CRD42021271050.