RT Journal Article
SR Electronic
T1 Systematic review protocol of the effectiveness of HIV prevention interventions for reducing risky sexual behaviour among youth globally
JF BMJ Open
JO BMJ Open
FD British Medical Journal Publishing Group
SP e056929
DO 10.1136/bmjopen-2021-056929
VO 12
IS 5
A1 Fungai Mbengo
A1 Maggie Zgambo
A1 Ebenezer Afrifa-Yamoah
A1 Fatch Welcome Kalembo
A1 Takanori Honda
A1 Yoko Shimpuku
A1 Sanmei Chen
YR 2022
UL http://bmjopen.bmj.com/content/12/5/e056929.abstract
AB Introduction Human immunodeficiency virus (HIV) prevention interventions focused at reducing risky sexual behaviours are an important strategy for preventing HIV infection among youth (15–24 years) who continue to be vulnerable to the disease. This systematic review aims to synthesise current global evidence on the effectiveness of HIV prevention interventions for reducing risky sexual behaviour among youth in the last decade.Methods and analysis MEDLINE/PubMed, EMBASE, PsychINFO, ProQuest Central, CINAHL and Web of Science databases, ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform and reference lists of included studies and systematic reviews on effectiveness of HIV prevention interventions for reducing risky sexual behaviour among youth will be searched for articles published from August 2011 to August 2021. Eligible studies will be longitudinal studies including randomised controlled trials and quasi-experimental studies that examined the effectiveness of HIV prevention interventions among youth populations (15–24 years) with risky sexual behaviour as a primary or secondary outcome. Study selection and quality assessment will be undertaken independently by three reviewers and disagreements will be resolved through consensus. Data analysis will be undertaken using RevMan software V.5.3.3. A random effects meta-analysis will be conducted to report heterogeneous data where statistical pooling is achievable. We will use I2 statistics to test for heterogeneity. Where appropriate, a funnel plot will be generated to assess publication bias. Where statistical pooling is unachievable, the findings will be reported in a narrative form, together with tables and figures to assist in data presentation if required. Reporting of the systematic review will be informed by Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.Ethics and dissemination Ethical approval is not required. Findings of the systematic review will be published in a peer-reviewed journal. The findings will be of interest to researchers, healthcare practitioners and policymakers.PROSPERO registration number CRD42021271774.