RT Journal Article SR Electronic T1 Clinical practice guideline recommendations for pediatric injury care: protocol for a systematic review JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e060054 DO 10.1136/bmjopen-2021-060054 VO 12 IS 4 A1 Lynne Moore A1 Gabrielle Freire A1 Anis Ben Abdeljelil A1 Melanie Berube A1 Pier-Alexandre Tardif A1 Eunice Gnanvi A1 Henry Thomas Stelfox A1 Marianne Beaudin A1 Sasha Carsen A1 Antonia Stang A1 Suzanne Beno A1 Matthew Weiss A1 Melanie Labrosse A1 Roger Zemek A1 Isabelle J Gagnon A1 Emilie Beaulieu A1 Simon Berthelot A1 Terry Klassen A1 Alexis F Turgeon A1 François Lauzier A1 Ian Pike A1 Alison Macpherson A1 Belinda J Gabbe A1 Natalie Yanchar YR 2022 UL http://bmjopen.bmj.com/content/12/4/e060054.abstract AB Introduction Evidence suggests the presence of deficiencies in the quality of care provided to up to half of all paediatric trauma patients in Canada, the USA and Australia. Lack of adherence to evidence-based recommendations may be driven by lack of knowledge of clinical practice guidelines (CPGs), heterogeneity in recommendations or concerns about their quality. We aim to systematically review CPG recommendations for paediatric injury care and appraise their quality.Methods and analysis We will identify CPG recommendations through a comprehensive search strategy including Medical Literature Analysis and Retrieval System Online, Excerpta Medica dataBASE, Cochrane library, Web of Science, ClinicalTrials and websites of organisations publishing recommendations on paediatric injury care. We will consider CPGs including at least one recommendation targeting paediatric injury populations on any diagnostic or therapeutic intervention from the acute phase of care with any comparator developed in high-income countries in the last 15 years (January 2007 to a maximum of 6 months prior to submission). Pairs of reviewers will independently screen titles, abstracts and full text of eligible articles, extract data and evaluate the quality of CPGs and their recommendations using Appraisal of Guidelines Research and Evaluation (AGREE) II and AGREE Recommendations Excellence instruments, respectively. We will synthesise evidence on recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence-to-Decision framework and present results within a recommendations matrix.Ethics and dissemination Ethics approval is not a requirement as this study is based on available published data. The results of this systematic review will be published in a peer-reviewed journal, presented at international scientific meetings and distributed to healthcare providers.PROSPERO registration number International Prospective Register of Systematic Reviews (CRD42021226934).