PT  - JOURNAL ARTICLE
AU  - Lynne Moore
AU  - Gabrielle Freire
AU  - Anis Ben Abdeljelil
AU  - Melanie Berube
AU  - Pier-Alexandre Tardif
AU  - Eunice Gnanvi
AU  - Henry Thomas Stelfox
AU  - Marianne Beaudin
AU  - Sasha Carsen
AU  - Antonia Stang
AU  - Suzanne Beno
AU  - Matthew Weiss
AU  - Melanie Labrosse
AU  - Roger Zemek
AU  - Isabelle J Gagnon
AU  - Emilie Beaulieu
AU  - Simon Berthelot
AU  - Terry Klassen
AU  - Alexis F Turgeon
AU  - François Lauzier
AU  - Ian Pike
AU  - Alison Macpherson
AU  - Belinda J Gabbe
AU  - Natalie Yanchar
TI  - Clinical practice guideline recommendations for pediatric injury care: protocol for a systematic review
AID  - 10.1136/bmjopen-2021-060054
DP  - 2022 Apr 01
TA  - BMJ Open
PG  - e060054
VI  - 12
IP  - 4
4099  - http://bmjopen.bmj.com/content/12/4/e060054.short
4100  - http://bmjopen.bmj.com/content/12/4/e060054.full
SO  - BMJ Open2022 Apr 01; 12
AB  - Introduction Evidence suggests the presence of deficiencies in the quality of care provided to up to half of all paediatric trauma patients in Canada, the USA and Australia. Lack of adherence to evidence-based recommendations may be driven by lack of knowledge of clinical practice guidelines (CPGs), heterogeneity in recommendations or concerns about their quality. We aim to systematically review CPG recommendations for paediatric injury care and appraise their quality.Methods and analysis We will identify CPG recommendations through a comprehensive search strategy including Medical Literature Analysis and Retrieval System Online, Excerpta Medica dataBASE, Cochrane library, Web of Science, ClinicalTrials and websites of organisations publishing recommendations on paediatric injury care. We will consider CPGs including at least one recommendation targeting paediatric injury populations on any diagnostic or therapeutic intervention from the acute phase of care with any comparator developed in high-income countries in the last 15 years (January 2007 to a maximum of 6 months prior to submission). Pairs of reviewers will independently screen titles, abstracts and full text of eligible articles, extract data and evaluate the quality of CPGs and their recommendations using Appraisal of Guidelines Research and Evaluation (AGREE) II and AGREE Recommendations Excellence instruments, respectively. We will synthesise evidence on recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence-to-Decision framework and present results within a recommendations matrix.Ethics and dissemination Ethics approval is not a requirement as this study is based on available published data. The results of this systematic review will be published in a peer-reviewed journal, presented at international scientific meetings and distributed to healthcare providers.PROSPERO registration number International Prospective Register of Systematic Reviews (CRD42021226934).