RT Journal Article SR Electronic T1 Primary care for patients with respiratory tract infection before and early on in the COVID-19 pandemic: an observational study in 16 European countries JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e049257 DO 10.1136/bmjopen-2021-049257 VO 11 IS 7 A1 van der Velden, Alike W A1 Bax, Eva A A1 Bongard, Emily A1 Munck Aabenhus, Rune A1 Anastasaki, Marilena A1 Anthierens, Sibyl A1 Balan, Anca A1 Böhmer, Femke A1 Bruno, Pascale A1 Chlabicz, Slawomir A1 Coenen, Samuel A1 Colliers, Annelies A1 Emmerich, Susanne A1 Garcia-Sangenis, Ana A1 Ghazaryan, Hrachuhi A1 van der Linde, Sanne R A1 Malania, Lile A1 Pauer, József A1 Tomacinschii, Angela A1 Tonkin-Crine, Sarah A1 Vellinga, Akke A1 Zastavnyy, Ihor A1 Verheij, Theo A1 Goossens, Herman A1 Butler, Christopher C YR 2021 UL http://bmjopen.bmj.com/content/11/7/e049257.abstract AB Objective To describe primary health care (consultation characteristics and management) for patients contacting their general practitioner (GP) with a respiratory tract infection (RTI) early on in the COVID-19 pandemic in contrasting European countries, with comparison to prepandemic findings.Setting Primary care in 16 countries (79 practices), when no routine SARS-CoV-2 testing was generally available.Design and participants Before (n=4376) and early in the pandemic (n=3301), patients with RTI symptoms were registered in this prospective audit study.Outcome measures Consultation characteristics (type of contact and use of PPE) and management characteristics (clinical assessments, diagnostic testing, prescribing, advice and referral) were registered. Differences in these characteristics between countries and between pandemic and prepandemic care are described.Results Care for patients with RTIs rapidly switched to telephone/video consultations (10% in Armenia, 91% in Denmark), and when consultations were face-to-face, GPs used PPE during 97% (95% CI 96% to 98%) of contacts. Laboratory testing for SARS-CoV-2 in primary care patients with RTIs was rapidly implemented in Denmark (59%) and Germany (31%), while overall testing for C reactive protein decreased. The proportion of patients prescribed antibiotics varied considerably between countries (3% in Belgium, 48% in UK) and was lower during the pandemic compared with the months before, except for Greece, Poland and UK. GPs provided frequent and varied COVID-related advice and more frequently scheduled a follow-up contact (50%, 95% CI 48% to 52%). GPs reported a slightly higher degree of confidence in the likely effectiveness of their management in face-to-face (73% (very) confident, 95% CI 71% to 76%) than in virtual consultations (69%, 95% CI 67% to 71%).Conclusions Despite between-country variation in consultation characteristics, access to SARS-CoV-2 laboratory testing and medication prescribing, GPs reported a high degree of confidence in managing their patients with RTIs in the emerging pandemic. Insight in the highly variable pandemic responses, as measured in this multicountry audit, can aid in fine-tuning national action and in coordinating a pan-European response during future pandemic threats.Data are available upon reasonable request. Additional to the items reported here, outcomes for all items in the Case Report Form (online supplemental appendix 1) are available for all countries, or per individual country, upon request, explaining research question and methods, from the first author (AWvdV) who will seek agreement from the core research team.