RT Journal Article SR Electronic T1 Weight gain in Chinese youth during a 4-month COVID-19 lockdown: a retrospective observational study JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e052451 DO 10.1136/bmjopen-2021-052451 VO 11 IS 7 A1 Yaoshan Dun A1 Jeffrey W. Ripley-Gonzalez A1 Nanjiang Zhou A1 Baiyang You A1 Qiuxia Li A1 Hui Li A1 Wenliang Zhang A1 Randal J. Thomas A1 Thomas P. Olson A1 Jie Liu A1 Yuchen Dong A1 Suixin Liu YR 2021 UL http://bmjopen.bmj.com/content/11/7/e052451.abstract AB Objectives To observe the weight change in Chinese youth during a 4-month COVID-19 lockdown, and the association between weight change and mental health, physical activity and sedentary time changes, and dietary habits.Design A retrospective observational study.Settings Two universities located in Zhejiang and Hunan provinces, China.Participants This study enrolled 12 889 college students whose body weight was measured before the lockdown (1 December 2019–20 January 2020) at the two universities, and reported their weight measured at home or community after the end of the lockdown (1–23 May 2020) via an online follow-up questionnaire.Primary and secondary outcome measures The primary outcome was the weight change in Chinese youth during a 4-month lockdown resulting from the COVID-19 pandemic. The secondary outcomes were the relationships of weight change to COVID-19-related stress, depression, anxiety, physical activity and sedentary time changes, and dietary habits.Results Participants’ ages ranged from 17 to 27 years (M=19, SD=1) with 80.2% identified as female. The average absolute and relative changes in body weight were 2.6 (95% CI 2.0 to 3.2)) kg and 4.2% (95% CI 4.0% to 4.3%) for men, and 2.1 (1.9 to 2.4) kg and 4.2% (95% CI 3.9% to 4.4%) for women. An increase in overweight and obese individuals according to Asian cut-off points as a demographic percentage by 4.5% and 2.7% and 4.8% and 3.4% in men and women, respectively (P<0.001), was observed. Weight gain was significantly associated with increased sedentary time and an increase in COVID-19-related stress and depression score.Conclusion The present study’s results suggest that the risk of weight gain in Chinese youth during the lockdown increased and that strategies to decrease sedentary time and improve mental health may be warranted to mitigate weight gain during and after the COVID-19 pandemic.Data are available upon reasonable request. The data that support the findings of this study are available on request from the corresponding author, SL.