PT  - JOURNAL ARTICLE
AU  - Andreas D Haas
AU  - Cordelia Kunzekwenyika
AU  - Stefanie Hossmann
AU  - Josphat Manzero
AU  - Janneke van Dijk
AU  - Ronald Manhibi
AU  - Ruth Verhey
AU  - Andreas Limacher
AU  - Per M von Groote
AU  - Ethel Manda
AU  - Michael A Hobbins
AU  - Dixon Chibanda
AU  - Matthias Egger
ED  - ,
TI  - Symptoms of common mental disorders and adherence to antiretroviral therapy among adults living with HIV in rural Zimbabwe: a cross-sectional study
AID  - 10.1136/bmjopen-2021-049824
DP  - 2021 Jul 01
TA  - BMJ Open
PG  - e049824
VI  - 11
IP  - 7
4099  - http://bmjopen.bmj.com/content/11/7/e049824.short
4100  - http://bmjopen.bmj.com/content/11/7/e049824.full
SO  - BMJ Open2021 Jul 01; 11
AB  - Objectives To examine the proportion of people living with HIV who screen positive for common mental disorders (CMD) and the associations between CMD and self-reported adherence to antiretroviral therapy (ART).Setting Sixteen government-funded health facilities in the rural Bikita district of Zimbabwe.Design Cross-sectional study.Participants HIV-positive non-pregnant adults, aged 18 years or older, who lived in Bikita district and had received ART for at least 6 months.Outcome measures The primary outcome was the proportion of participants screening positive for CMD defined as a Shona Symptoms Questionnaire score of 9 or greater. Secondary outcomes were the proportion of participants reporting suicidal ideation, perceptual symptoms and suboptimal ART adherence and adjusted prevalence ratios (aPR) for factors associated with CMD, suicidal ideation, perceptual symptoms and suboptimal ART adherence.Results Out of 3480 adults, 18.8% (95% CI 14.8% to 23.7%) screened positive for CMD, 2.7% (95% CI 1.5% to 4.7%) reported suicidal ideations, and 1.5% (95% CI 0.9% to 2.6%) reported perceptual symptoms. Positive CMD screens were more common in women (aPR 1.67, 95% CI 1.19 to 2.35) than in men and were more common in adults aged 40–49 years (aPR 1.47, 95% CI 1.16 to 1.85) or aged 50–59 years (aPR 1.51, 95% CI 1.05 to 2.17) than in those 60 years or older. Positive CMD screen was associated with suboptimal adherence (aPR 1.53; 95% CI 1.37 to 1.70).Conclusions A substantial proportion of people living with HIV in rural Zimbabwe are affected by CMD. There is a need to integrate mental health services and HIV programmes in rural Zimbabwe.Trial registration number NCT03704805.Data are available on reasonable request. Data cannot be made available online because of legal and ethical restrictions. To request data, readers may contact IeDEA for consideration by filling out the online form available at https://www.iedea-sa.org/contact-us/