RT Journal Article SR Electronic T1 Community psychosocial music intervention (CHIME) to reduce antenatal common mental disorder symptoms in The Gambia: a feasibility trial JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e040287 DO 10.1136/bmjopen-2020-040287 VO 10 IS 11 A1 Katie Rose M Sanfilippo A1 Bonnie McConnell A1 Victoria Cornelius A1 Buba Darboe A1 Hajara B Huma A1 Malick Gaye A1 Hassoum Ceesay A1 Paul Ramchandani A1 Ian Cross A1 Vivette Glover A1 Lauren Stewart YR 2020 UL http://bmjopen.bmj.com/content/10/11/e040287.abstract AB Objectives Examine the feasibility of a Community Health Intervention through Musical Engagement (CHIME) in The Gambia to reduce common mental disorder (CMD) symptoms in pregnant women.Design Feasibility trial testing a randomised stepped-wedge cluster design.Setting Four local antenatal clinics.Participants Women who were 14–24 weeks pregnant and spoke Mandinka or Wolof were recruited into the intervention (n=50) or control group (n=74).Intervention Music-based psychosocial support sessions designed and delivered by all-female fertility societies. Sessions lasted 1 hour and were held weekly for 6 weeks. Delivered to groups of women with no preselection. Sessions were designed to lift mood, build social connection and provide health messaging through participatory music making. The control group received standard antenatal care.Outcomes Demographic, feasibility, acceptability outcomes and the appropriateness of the study design were assessed. Translated measurement tools (Self-Reporting Questionnaire (SRQ-20); Edinburgh Postnatal Depression Scale (EPDS)) were used to assess CMD symptoms at baseline, post-intervention and 4-week follow-up.Results All clinics and 82% of women approached consented to take part. A 33% attrition rate across all time points was observed. 72% in the intervention group attended at least three sessions. Audio and video analysis confirmed fidelity of the intervention and a thematic analysis of participant interviews demonstrated acceptability and positive evaluation. Results showed a potential beneficial effect with a reduction of 2.13 points (95% CI (0.89 to 3.38), p<0.01, n=99) on the SRQ-20 and 1.98 points (95% CI (1.06 to 2.90), p<0.01, n=99) on the EPDS at the post-intervention time point for the intervention group compared with standard care.Conclusion Results demonstrate that CHIME is acceptable and feasible in The Gambia. To our knowledge, CHIME is the first example of a music-based psychosocial intervention to be applied to perinatal mental health in a low- and middle-income country context.Trial registration number Pan African Clinical Trials Registry (PACTR201901917619299).