RT Journal Article
SR Electronic
T1 Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in Japan
JF BMJ Open
JO BMJ Open
FD British Medical Journal Publishing Group
SP e033822
DO 10.1136/bmjopen-2019-033822
VO 10
IS 11
A1 Asami Okada
A1 Yohei Okada
A1 Hiromichi Narumiya
A1 Wataru Ishii
A1 Tetsuhisa Kitamura
A1 Toshio Osamura
A1 Ryoji Iiduka
YR 2020
UL http://bmjopen.bmj.com/content/10/11/e033822.abstract
AB Objectives To examine the association between body temperature (BT) on hospital arrival and in-hospital mortality among paediatric trauma patients.Design A retrospective cohort study.Setting Japan Trauma Data Bank (JTDB, which is a nationwide, prospective, observational trauma registry with data from 235 hospitals).Participants Paediatric trauma patients <16 years old who were transferred directly from the scene of injury to the hospital and registered in the JTDB from January 2004 to December 2017 were included. We excluded patients >16 years old and those who developed cardiac arrest before or on hospital arrival.Primary outcome The association between BT on hospital arrival and in-hospital mortality. We conducted multivariate logistic regression analyses to calculate the adjusted ORs, with their 95% CIs, of the association between BT and in-hospital mortality.Results A total of 9012 patients were included (median age: 9 years (IQR, 6.0–13.0 years), mortality: 2.5% (mortality number was 226 in total 9012 patients)). In the multivariate logistic regression analysis, the corresponding adjusted ORs of BT <36.0°C and BT ≥37.0°C, relative to a BT of 36°C–36.9°C, for in-hospital mortality were 2.83 (95% CI: 1.85 to 4.33) and 0.93 (95% CI: 0.53 to 1.63), respectively.Conclusions In paediatric patients with hypothermia (BT <36.0°C) on hospital arrival, a clear association with in-hospital mortality was observed; no such association was observed between higher BT values (≥37.0°C) and outcomes.