RT Journal Article SR Electronic T1 Social, biological, behavioural and psychological factors related to physical activity during early pregnancy in the Screening for Pregnancy Endpoints (Cork, Ireland) cohort study JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e025003 DO 10.1136/bmjopen-2018-025003 VO 9 IS 6 A1 Caragh Flannery A1 Darren Dahly A1 Molly Byrne A1 Ali Khashan A1 Sheena McHugh A1 Louise C Kenny A1 Fionnuala McAuliffe A1 Patricia M Kearney YR 2019 UL http://bmjopen.bmj.com/content/9/6/e025003.abstract AB Objective The aim of this study was to identify the social, biological, behavioural and psychological factors related to physical activity (PA) in early pregnancy.Design This is a secondary analysis of data from a prospective cohort study.Setting The study was conducted in Cork, Ireland.Participants Nulliparous women with singleton pregnancies were recruited and then interviewed at 15±1 weeks’ gestation.Primary and secondary outcomes The biopsychosocial model identified factors including social (age), biological (body mass index), behavioural (diet) and psychological (anxiety) at 15±1 weeks’ gestation. PA subgroups were identified based on a latent class analysis of their responses to a set of questions about the amount and intensity of activity they were engaging in during the pregnancy. Associations were estimated with multivariable multinomial logistic regression models.Results From a total of 2579, 1774 (69%) women were recruited; ages ranged from 17 to 45 years. Based on a combination of model fit, theoretical interpretability and classification quality, the latent class analyses identified three PA subgroups: low PA (n=393), moderate PA (n=960) and high PA (n=413). The fully adjusted model suggests non-smokers, and consumers of fruit and vegetables were more likely to be in the high PA subgroup (vs low). Women with more than 12 years of schooling and a higher socioeconomic status were more likely to be in the moderate PA subgroup (vs low).Conclusion The findings highlight potential links between PA, a low education level and a low socioeconomic background. These factors should be considered for future interventions to improve low PA levels during pregnancy.Trial registration number ACTRN 12607000551493.