PT  - JOURNAL ARTICLE
AU  - José Joaquín Mira
AU  - Irene Carrillo
AU  - María Teresa Gea Velázquez de Castro
AU  - Carmen Silvestre
AU  - Guadalupe Olivera
AU  - Johanna Caro-Mendivelso
AU  - Pastora Pérez-Pérez
AU  - Yolanda Agra
AU  - Ana Mª Fernández
AU  - Jesús Maria Aranaz-Andrés
ED  - ,
TI  - SOBRINA Spanish study—analysing the frequency, cost and adverse events associated with overuse in primary care: protocol for a retrospective cohort study
AID  - 10.1136/bmjopen-2018-023399
DP  - 2019 Mar 01
TA  - BMJ Open
PG  - e023399
VI  - 9
IP  - 3
4099  - http://bmjopen.bmj.com/content/9/3/e023399.short
4100  - http://bmjopen.bmj.com/content/9/3/e023399.full
SO  - BMJ Open2019 Mar 01; 9
AB  - Introduction Several institutions and quality national agencies have fostered the creation of recommendations on what not to do to reduce overuse in clinical practice. In primary care, their impact has hardly been studied. The frequency of adverse events (AEs) associated with doing what must not be done has not been analysed, either. The aim of this study is to measure the frequency of overuse and AEs associated with doing what must not be done (commission errors) in primary care and their cost.Methods and analysis A coordinated, multicentric, national project. A retrospective cohort study using computerised databases of primary care medical records from national agencies and regional health services will be conducted to analyse the frequency of the overuse due to ignore the do-not-do recommendations, and immediately afterwards, depending on their frequency, a representative random sample of medical records will be reviewed with algorithms (triggers) that determine the frequency of AEs associated with these recommendations. Cost will determine by summation of the direct costs due to the consultation, pharmacy, laboratory and imaging activities according to the cases.Ethics and dissemination The study protocol has been approved by the Ethics Committee of Primary Care Research of the Valencian Community. We aim to disseminate the findings through international peer-reviewed journals and on the website (http://www.nohacer.es/). Outcomes will be used to incorporate algorithms into the electronic history to assist in making clinical decisions.Trial registration number NCT03482232; Pre-results.