RT Journal Article SR Electronic T1 Is prolonged sitting at work associated with the time course of neck–shoulder pain? A prospective study in Danish blue-collar workers JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e012689 DO 10.1136/bmjopen-2016-012689 VO 6 IS 11 A1 David M Hallman A1 Nidhi Gupta A1 Marina Heiden A1 Svend Erik Mathiassen A1 Mette Korshøj A1 Marie Birk Jørgensen A1 Andreas Holtermann YR 2016 UL http://bmjopen.bmj.com/content/6/11/e012689.abstract AB Objectives This study aimed to determine the extent to which objectively measured sitting time at work is associated with the course of neck–shoulder pain across 1 year in blue-collar workers.Methods Data were analysed from 625 blue-collar workers in the Danish PHysical ACTivity cohort with Objective measurements (DPHACTO) cohort study (2012–2013). Objective data on sitting time were collected at baseline using accelerometry. Self-reported pain intensity (numeric rating scale 0–10) in the neck–shoulder region was registered for 1 year using repeated text messages (14 in total). Linear mixed models were used to determine the relationship between per cent time in sitting at work and trajectories of neck–shoulder pain, with and without adjustment for demographic, occupational and lifestyle factors, and baseline pain intensity.Results More sitting time at work was associated with a faster decline in pain intensity over 12 months, as indicated by a statistically significant effect of sitting on pain trajectories in the crude (p=0.020) and fully adjusted models (p=0.027).Conclusions In blue-collar workers, more sitting time at work was associated with a favourable development of pain intensity over time. The relationship between sitting at work and pain needs further investigation before explicit recommendations and guidelines on sedentary behaviour among blue-collar workers can be developed.