174 e-Letters

published between 2010 and 2013

  • Leem Surveys on Attractiveness of France for International Clinical Trials
    Claire Sibenaler

    Thank you for this work which is very helpful for clinical trials site selection. We would like to inform about a work done in France on Clinical Research Attractiveness since 2002, and published early 2013 in Therapie Journal (Therapie 2013 Janvier-Fevrier;68 (1):1-18). A new Survey is on-going and the results will be available at the end of 2014 and then published. The abstract of the last publication is: Since 2002, th...

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  • The authors' reply leaves unresolved the critical question of primary bed-sharing
    Elizabeth S. Bernstein

    In their August 1, 2013 reply letter, the authors characterize as a misunderstanding the conclusion of a 2012 meta-analysis (1) -- using many of the same databases and with one of the same co-authors as the instant study -- that only non-routine bed-sharing is associated with an increased risk of SIDS. In this way they dismiss a critical limitation of their own study, one which calls fundamentally into question the soundn...

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  • Errata of paper Odland ML, Strand K, Nordbo SA, et al.
    Maria L. Odland

    The following corrections should be included:

    Table 1: Mean age is given as 29.8. It should be given as SD 4.5 in the parenthesis, not 4 to 5.

    Table 3: Age group is supposed to be 25-30, not 5-30.

    Additionally, in the results section of the abstract line 8, women with high education do not have their CMV-IgG seroprevalence given in a parenthesis. It is supposed to be 52.0%.

    Conflict o...

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  • Determining the direction of effect
    Tony Robertson

    I was interested to read Callander et al's recent article entitled 'Chronic health conditions and poverty: a cross-sectional study using a multidimensional poverty measure'. While the study is of high quality, I would argue that the authors have been remiss to exclude the possibility that it is just as likely that poverty is impacting on health, and not just poorer health leading to increased poverty. Given that the Surv...

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  • Comment on the article: Acute exacerbation (AE) in rheumatoid arthritis associated interstitial lung disease: a retrospective case control study.
    Jorge Rojas-Serrano

    Regarding the article of Hozumi H et. al. (1) I am concerned about the conclusions obtained with an invalid analysis of the data. Hazard ratios (HR) are not the appropriate measure of strength of association in the information presented by Hozumi et. al. First, it seems that patients received different treatments during follow up, in order to correctly use Cox regression analysis to obtain HR, patients must have being r...

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  • Adherence to antiretroviral drug therapy in adult patients who are HIV-positive in Northwest Ethiopia: a study protocol
    Kebede A. Beyene

    In their proposed study protocol of Adherence to ART among HIV positive patients in North West Ethiopia, Bezabhe et al properly noted the scarcity of information on determinants of long-term adherence to ART medications in Ethiopian context. Given the importance of adherence to long term treatment outcomes, understanding its determinants can be beneficial to improve the quality of healthcare provision to patients and min...

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  • Re:Reply to Rapuch et al.
    Peter K MacCallum

    We thank Sarah Rapuch and colleagues for their interest in our article.

    We agree that the expressed units for estimated creatinine clearance (eCrCl based on the Cockcroft-Gault equation) and estimated glomerular filtration rate (eGFR based on the 4-variable MDRD equation) are different but disagree with the conclusions they draw from this. With regard to points 1,2 and 4, whatever the advantages or disadvantages...

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  • Reply to MacCallum et al.
    Sarah Rapuch

    To the editor, We read with interest the article entitled "Patient safety and estimation of renal function in patients prescribed new oral anticoagulants for stroke prevention in atrial fibrillation: a cross-sectional study" by MacCallum et al. (1). Although this article shows well the difficulties encountered by physicians in prescribing the new oral anticoagulants dabigatran and rivaroxaban in the elderly and/or in pat...

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  • Re:Response to "Specificity and sensitivity of transcranial sonography of the substantia nigra in the diagnosis of Parkinson's disease: prospective cohort study in 196 patients"
    Wim E.J. Weber

    We would like to thank drs Mahlknecht, Seppi, and Berg for compliments on a study well designed and executed.

    They do, however, raise two major and one minor criticism to our study.

    Firstly, the DAT-SPECT data in our study were not in accordance with the clinical data, suggesting 'that clinical classification of the patients was suboptimal'. Secondly, the TCS data were disappointing, because, among o...

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  • The surgical safety checklist-mainly a challenge for anaesthesia mortality in low-income countries?
    Gregor Pollach

    Working on a daily basis in the theatres of the largest hospital in a low-income country (Malawi) we were pleased to read the study of Aveling and colleagues [1]. They demonstrated in a clear, quite comprehensive and critical manner challenges involved with the surgical safety checklist in resource poor situations.

    Continuously experiencing the real life situation in Africa we do think that there is an important...

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