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Effects of short-term smoking on lung function and airway hyper-responsiveness in young patients with untreated intermittent adult-onset asthma: retrospective cross-sectional study at a primary–tertiary care hospital in Japan
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  • Published on:
    Observation at the right time
    • Hirohito Takata, Pulmonologist Hyogo Prefectural Amagasaki General Medical Center
    • Other Contributors:
      • Yuki Kataoka, Pulmonologist

    Dear editor,

    We read with great interest the article by Kentaro Watai et al. They describe Short-term active smoking in early adulthood may be associated with decreased lung function and AHR, even in patients with intermittent adult-onset asthma. However we would like to make one comment.

    There was a period from the first visits to a histamine airway challenge test. If never smokers were receiving treatment by the time of the test, ther AHR would be lower than expected.[1]This information bias will weaken their conclusion.

    1. Haahtela T, Jarvinen M, Kava T, et al : Efects of reducing or discontinuing inhaled budesonide in patients with mild asthma. N Engl J Med 1994 ; 331 : 700―705.

    Conflict of Interest:
    None declared.