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High prevalence of hyperuricaemia and its impact on non-valvular atrial fibrillation: the cross-sectional Guangzhou (China) Heart Study
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    RE: High prevalence of hyperuricaemia and its impact on non-valvular atrial fibrillation: the cross-sectional Guangzhou (China) Heart Study

    Lin et al. conducted across-sectional study to evaluate the relationship between the prevalence of hyperuricaemia (HUA) and non-valvular atrial fibrillation (NVAF) (1). Age, living in urban areas, alcohol consumption, central obesity, elevated fasting plasma glucose level, elevated blood pressure, lower high-density lipoprotein cholesterol level and elevated triglycerides level were significantly associated with increased risk of HUA, and HUA were at higher risk for NVAF. Regarding sex difference, serum uric acid level had a modest predictive value for NVAF in women. I have some concerns about their study.

    First, Tu et al. conducted a prospective study to evaluate the risk of gout in patients with alcohol-related diseases and alcohol dependence syndrome (2). Alcohol-related diseases were significantly associated with gout risk, and severe alcohol-dependent patients were significantly associated with an increased risk of gout. The authors recommended that alcohol use assessment and measures to prevent alcohol dependence in patients with gout. I agree with their recommendation, which would partly lead to prevent NVAF.

    Second, Yu et al. presented strategies to improve gout/hyperuricemia management for preventing acute arthritis attacks, cardiovascular disease, kidney disease, and other urate-related disorders (3). Alcohol consumption is closely related to gout/hyperuricemia, and psycho-social factors should also be considered for the management.

    Third, Ku...

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    Conflict of Interest:
    None declared.