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Public health
Cohort profile
Cohort profile: the Lanxi Cohort study on obesity and obesity-related non-communicable diseases in China
  1. Chen Wei1,2,
  2. Sunyue Ye1,2,
  3. Yuan Ru1,2,
  4. Da Gan1,2,
  5. Weifang Zheng3,
  6. Chao Huang1,2,
  7. Lijin Chen1,2,
  8. Peng Gao1,2,
  9. Jiayu Li1,2,
  10. Min Yang1,2,
  11. Fei Yang1,2,
  12. Xueyin Zhao1,2,
  13. Shankuan Zhu1,2
  1. 1 Department of Nutrition and Food Hygiene, School of Public Health,School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
  2. 2 Chronic Disease Research Institute, School of Public Health, Zhejiang University, Hangzhou, Zhejiang Province, China
  3. 3 Lanxi Red CrossHospital, Lanxi, Zhejiang Province, China
  1. Correspondence to Dr Shankuan Zhu; zsk{at}zju.edu.cn

Abstract

Purpose The Lanxi Cohort was established to systematically investigate the aetiology and interplay of body fat distribution and multiple factors with obesity and obesity-related non-communicable diseases in China.

Participants The baseline investigation of the Lanxi Cohort study took place between June 2015 and August 2017 in Lanxi, Zhejiang Province, China. Permanent residents from one urban community and four rural villages were involved in this study. The baseline investigation included questionnaire survey, physical examination, dual-energy X-ray absorptiometry (DXA) scan, blood samples collection and traditional Chinese medicine (TCM) inquiry.

Findings to data A total of 5132 participants, aged 18 to 80 years, were recruited at baseline; among them, 38.7% were men and 64.8% were from the urban area. The mean age was 53.04±12.77 years. The completion rates of physical examination, DXA scan, blood collection and TCM inquiry were 99.9%, 98.5%, 99.9% and 96.5%, respectively. The mean body mass index (BMI) was 23.42±3.20 kg/m2 with 8.1% of the study population being obese (BMI ≥28 kg/m2). The crude prevalence of hypertension, diabetes and metabolic syndrome were 34.9%, 10.0% and 30.4%, respectively.

Future plans All participants will be monitored annually for cause-specific mortality and morbidity and hospital admission and will be followed up by in-person survey every 4 years. The baseline population is considered to expand in the future depending on the availability of funding support.

Ethics approval This study was approved by the Ethical Committee of the School of Public Health, Zhejiang University.

  • epidemiology
  • public health
  • obesity
  • cohort study
  • non-communicable disease
  • body composition

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

https://doi.org/10.1136/bmjopen-2018-025257

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    Footnotes

    • Contributors SZ conceived and designed the study. CW and DG analysed the data. CW and SZ drafted the manuscript. SZ, CW, SY, YR, DG, WZ, CH, LC, PG, JL, MY, FY and XZ provided comments and revised the manuscript. All authors read and approved the final manuscript.

    • Funding This study was supported by the grant from the Cyrus Tang Foundation (419600-11102), with additional grants from the China Medical Board (CMB) Collaborating Program (15-216 and 12-108).

    • Disclaimer The depiction of boundaries on the map(s) in this article do not imply the expression of any opinion whatsoever on the part of BMJ (or any member of its group) concerning the legal status of any country, territory, jurisdiction or area or of its authorities. The map(s) are provided without any warranty of any kind, either express or implied.

    • Competing interests None declared.

    • Ethics approval The ethics approval (NO: ZGL2012-12) was provided by the Ethics Committee of School of Public Health Zhejiang University.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Data sharing statement The data are not freely available, but we welcome any potential collaboration with other researchers. For further information, please email Shankuan Zhu at zsk@zju.edu.cn.

    • Collaborators The study data are currently not freely available; however, the research team welcomes all potential collaborations with other researchers. For further information, please email the corresponding author at zsk@zju.edu.cn.

    • Patient consent for publication Obtained.