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Obstetrics and gynaecology
Protocol
A double blind, randomised, placebo-controlled trial to evaluate the efficacy of metformin to treat preterm pre-eclampsia (PI2 Trial): study protocol

Authors

  • Catherine Cluver Department of Obstetrics and Gynaecology, Stellenbosch University Faculty of Science, Cape Town, Western Cape, South Africa Translational Obstetrics Group, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Susan P Walker Translational Obstetrics Group, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia Department of Obstetrics and Gynaecology, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Ben W Mol Department of Obstetrics and Gynaecology, School of Medicine, Monash University, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • David Hall Department of Obstetrics and Gynaecology, Stellenbosch University Faculty of Science, Matieland, Western Cape, South Africa PubMed articlesGoogle scholar articles
  • Richard Hiscock Department of Anaesthetics, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Fiona C Brownfoot Translational Obstetrics Group, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia Department of Obstetrics and Gynaecology, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Tu’uhevaha J Kaitu’u-Lino Translational Obstetrics Group and Department of Obstetrics and Gynaecology, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Stephen Tong Translational Obstetrics Group, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia Department of Obstetrics and Gynaecology, University of Melbourne, Mercy Hospital for Women, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Catherine Cluver; cathycluver{at}hotmail.com
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Citation

Cluver C, Walker SP, Mol BW, et al
A double blind, randomised, placebo-controlled trial to evaluate the efficacy of metformin to treat preterm pre-eclampsia (PI2 Trial): study protocol
BMJ Open 2019;9:e025809. doi: 10.1136/bmjopen-2018-025809

Publication history

  • Received August 2, 2018
  • Revised February 26, 2019
  • Accepted February 27, 2019
  • First published April 24, 2019.
Online issue publication 
February 14, 2023
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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.