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A cross-sectional study to assess prevalence and factors associated with mild cognitive impairment among older adults in an urban area of Kerala, South India
  1. Devi Mohan1,
  2. Thomas Iype2,
  3. Sara Varghese3,
  4. Anuja Usha3,
  5. Minu Mohan4
  1. 1 Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University - Malaysia Campus, Bandar Sunway, Malaysia
  2. 2 Department of Neurology, Government Medical College, Thiruvananthapuram, Kerala, India
  3. 3 Department of Community Medicine, Government Medical College, Kollam, Kerala, India
  4. 4 Department of Community Medicine, Government Medical College, Thiruvananthapuram, Kerala, India
  1. Correspondence to Dr Devi Mohan; devi.mohan{at}


Objectives To assess the prevalence and factors associated with mild cognitive impairment (MCI) among older adults in an urban area of South India.

Setting The study was conducted in the capital city of Thiruvananthapuram in the South Indian state of Kerala.

Participants The study participants were community-dwelling individuals aged 60 years and above.

Primary outcome measure MCI was the primary outcome measure and was defined using the criteria by European Alzheimer’s Disease Consortium. Cognitive assessment was done using the Malayalam version of Addenbrooke’s Cognitive Examination tool. Data were also collected on sociodemographic variables, self-reported comorbidities like hypertension and diabetes, lifestyle factors, depression, anxiety and activities of daily living.

Results The prevalence of MCI was found to be 26.06% (95% CI of 22.12 to 30.43). History of imbalance on walking (adjusted OR 2.75; 95 % CI of 1.46 to 5.17), presence of depression (adjusted OR 2.17, 95 % CI of 1.21 to 3.89), anxiety (adjusted OR 2.22; 95 % CI of 1.21 to 4.05) and alcohol use (adjusted OR 1.99; 95 % CI of 1.02 to 3.86) were positively associated with MCI while leisure activities at home (adjusted OR 0.33; 95 % CI of 0.11 to 0.95) were negatively associated.

Conclusion The prevalence of MCI is high in Kerala. It is important that the health system and the government take up urgent measures to tackle this emerging public health issue.

  • elderly
  • mild cognitive impairment
  • dementia

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  • Contributors DM and TI conceived the research idea. SV and AU contributed to refinement of idea. DM conducted the analysis and prepared the first draft. TI, SV, AU and MM contributed to the subsequent drafts. All the authors agreed to the final draft.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data are available.

  • Patient consent for publication Not required.

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