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Dog ownership and cardiovascular risk factors: a nationwide prospective register-based cohort study
  1. Mwenya Mubanga1,
  2. Liisa Byberg2,
  3. Agneta Egenvall3,
  4. Johan Sundström4,
  5. Patrik Karl Erik Magnusson5,
  6. Erik Ingelsson1,6,
  7. Tove Fall1
  1. 1 Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
  2. 2 Department of Surgical Sciences, Orthopedics, Uppsala University, Uppsala Universitet, Uppsala, Sweden
  3. 3 Division of Ruminant Medicine and Veterinary Epidemiology, Department of Clinical Sciences, Swedish University of Agricultural Science, Uppsala, Sweden
  4. 4 Department of Medical Sciences, Clinical Epidemiology, Uppsala University, Uppsala, Sweden
  5. 5 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  6. 6 Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford University, Stanford, California, USA
  1. Correspondence to Dr Tove Fall; tove.fall{at}medsci.uu.se

Footnotes

  • Contributors TF conceived the study and acquired funding. MM, AE, EI, JS and LB contributed to the design of the study. TF acquired the national data and PKEM is responsible for the Swedish Twin Registry data. MM performed data cleaning. MM and TF ran statistical analyses. MM drafted the manuscript and all authors reviewed the manuscript.

  • Funding The study was funded by the Agria Research Foundation and the Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS), grant number 2013-1673. TF has personal funding from the Goran Gustafsson foundation. The Swedish Twin Registry is managed by Karolinska Institutet and receives funding through the Swedish Research Council under the grant no 2017-00641.

  • Competing interests EI is a scientific advisor for Precision Wellness and Olink Proteomics for work unrelated to the present project.

  • Ethics approval The regional ethical review board in Stockholm, Sweden, approved the study (national study: 2012/1114-31/2, with amendment 2013-1687-32; TwinGene: 2007/644-31/2 and 2016/1392-31/1).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement The register data that support the findings of this study were made available by record-linkage with data from Statistics Sweden, the National Board of Health and Welfare, the Swedish Kennel Club, Swedish Board of Agriculture and the Swedish Twin Register. Restrictions apply to the availability of these data, which were used under license and ethical approval for the current study, and so are not publicly available. Data are however available from the authors upon reasonable request and with permission of the Regional Ethical Review Board in Stockholm, Sweden.

  • Presented at The results of this study were previously presented as a poster at the World Congress or Cardiology and Cardiovascular Health 2018 and an abstract was published in Global Heart Volume 13, Issue 4, December 2018, Page 483.

  • Patient consent for publication Not required.

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Footnotes

  • Contributors TF conceived the study and acquired funding. MM, AE, EI, JS and LB contributed to the design of the study. TF acquired the national data and PKEM is responsible for the Swedish Twin Registry data. MM performed data cleaning. MM and TF ran statistical analyses. MM drafted the manuscript and all authors reviewed the manuscript.

  • Funding The study was funded by the Agria Research Foundation and the Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS), grant number 2013-1673. TF has personal funding from the Goran Gustafsson foundation. The Swedish Twin Registry is managed by Karolinska Institutet and receives funding through the Swedish Research Council under the grant no 2017-00641.

  • Competing interests EI is a scientific advisor for Precision Wellness and Olink Proteomics for work unrelated to the present project.

  • Ethics approval The regional ethical review board in Stockholm, Sweden, approved the study (national study: 2012/1114-31/2, with amendment 2013-1687-32; TwinGene: 2007/644-31/2 and 2016/1392-31/1).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement The register data that support the findings of this study were made available by record-linkage with data from Statistics Sweden, the National Board of Health and Welfare, the Swedish Kennel Club, Swedish Board of Agriculture and the Swedish Twin Register. Restrictions apply to the availability of these data, which were used under license and ethical approval for the current study, and so are not publicly available. Data are however available from the authors upon reasonable request and with permission of the Regional Ethical Review Board in Stockholm, Sweden.

  • Presented at The results of this study were previously presented as a poster at the World Congress or Cardiology and Cardiovascular Health 2018 and an abstract was published in Global Heart Volume 13, Issue 4, December 2018, Page 483.

  • Patient consent for publication Not required.

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