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Mapping the preclinical to clinical evidence and development trajectory of the oncolytic virus talimogene laherparepvec (T-VEC): a systematic review

Authors

  • Manoj Lalu BLUEPRINT Translational Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada Department of Anesthesiology and Pain Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada Department of Cellular and Molecular Medicine, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Garvin J Leung BLUEPRINT Translational Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Yuan Yi Dong BLUEPRINT Translational Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Joshua Montroy BLUEPRINT Translational Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Claire Butler BLUEPRINT Translational Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Rebecca C Auer Department of Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada Cancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Dean A Fergusson BLUEPRINT Translational Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Dean A Fergusson; dafergusson{at}ohri.ca
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Citation

Lalu M, Leung GJ, Dong YY, et al
Mapping the preclinical to clinical evidence and development trajectory of the oncolytic virus talimogene laherparepvec (T-VEC): a systematic review

Publication history

  • Received January 30, 2019
  • Revised November 1, 2019
  • Accepted November 4, 2019
  • First published December 2, 2019.
Online issue publication 
December 02, 2019

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