Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol

Justin E Bekelman; Hien Lu; Stephanie Pugh; Kaysee Baker; Christine D Berg; Amy Berrington de Gonzalez; Lior Z Braunstein; Walter Bosch; Cynthia Chauhan; Susan Ellenberg; L Christine Fang; Gary M Freedman; Elizabeth A Hahn; B G Haffty; Atif J Khan; Rachel B Jimenez; Christy Kesslering; Bonnie Ky; Choonsik Lee; Hsiao-Ming Lu; Mark V Mishra; C Daniel Mullins; Robert W Mutter; Suneel Nagda; Mark Pankuch; Simon N Powell; Fred W Prior; Karen Schupak; Alphonse G Taghian; J Ben Wilkinson; Shannon M MacDonald; Oren Cahlon

doi:10.1136/bmjopen-2018-025556

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Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol

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Justin E Bekelman Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA PubMed articles Google scholar articles
Hien Lu Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA PubMed articles Google scholar articles
Stephanie Pugh American College of Radiology, Philadelphia, Pennsylvania, USA PubMed articles Google scholar articles
Kaysee Baker Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA PubMed articles Google scholar articles
Christine D Berg Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA PubMed articles Google scholar articles
Amy Berrington de Gonzalez Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA PubMed articles Google scholar articles
Lior Z Braunstein Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York city, New York, USA PubMed articles Google scholar articles
Walter Bosch Department of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA PubMed articles Google scholar articles
Cynthia Chauhan Mayo Clinic Minnesota, Rochester, Minnesota, USA PubMed articles Google scholar articles
Susan Ellenberg Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA PubMed articles Google scholar articles
L Christine Fang Department of Radiation Oncology, University of Washington School of Medicine, Seattle, Washington, USA PubMed articles Google scholar articles
Gary M Freedman Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA PubMed articles Google scholar articles
Elizabeth A Hahn Department of Medical Social Sciences, Northwestern University, Evanston, Illinois, USA PubMed articles Google scholar articles
B G Haffty Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA PubMed articles Google scholar articles
Atif J Khan Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York city, New York, USA PubMed articles Google scholar articles
Rachel B Jimenez Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
Christy Kesslering Northwestern Medicine Chicago Proton Center, Warrenville, Illinois, USA PubMed articles Google scholar articles
Bonnie Ky Cardio-Oncology Program, Division of Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA PubMed articles Google scholar articles
Choonsik Lee Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA PubMed articles Google scholar articles
Hsiao-Ming Lu Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
Mark V Mishra Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA PubMed articles Google scholar articles
C Daniel Mullins PHSR, University of Maryland School of Pharmacy, Baltimore, Maryland, USA PubMed articles Google scholar articles
Robert W Mutter Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA PubMed articles Google scholar articles
Suneel Nagda Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA PubMed articles Google scholar articles
Mark Pankuch Northwestern Medicine Chicago Proton Center, Warrenville, Illinois, USA PubMed articles Google scholar articles
Simon N Powell Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York city, New York, USA PubMed articles Google scholar articles
Fred W Prior Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA PubMed articles Google scholar articles
Karen Schupak Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York city, New York, USA PubMed articles Google scholar articles
Alphonse G Taghian Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
J Ben Wilkinson Provision Proton Therapy Center, Knoxville, Tennessee, USA PubMed articles Google scholar articles
Shannon M MacDonald Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
Oren Cahlon Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York city, New York, USA PubMed articles Google scholar articles
RadComp (Radiotherapy Comparative Effectiveness Consortium)
Google scholar articles

Correspondence to Dr Justin E Bekelman; bekelman{at}upenn.edu

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Bekelman JE, Lu H, Pugh S RadComp (Radiotherapy Comparative Effectiveness Consortium), et al

Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol

BMJ Open 2019;9:e025556. doi: 10.1136/bmjopen-2018-025556

Publication history

Received July 20, 2018
Revised February 7, 2019
Accepted July 26, 2019
First published October 15, 2019.

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May 31, 2023

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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